The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

by Ahmed, Syed Moiz, Ramani, Priya Dharshana, Wong, Stephen Qi Rong, Zhao, Xiaodan, Ivanyi-Nagy, Roland, Leong, Tang Choong, Chua, Clarinda, Li, Zhizhong, Hentze, Hannes, Tan, Iain BeeHuat, Yan, Jie, DasGupta, Ramanuj, Dröge, Peter
Published 2019

Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer

by Akıncılar, Semih Can, Chua, Joelle Yi Heng, Ng, Qin Feng, Chan, Claire Hian Tzer, Eslami-S, Zahra, Chen, Kaijing, Low, Joo-Leng, Arumugam, Surendar, Aswad, Luay, Chua, Clarinda, Tan, Iain Beehuat, DasGupta, Ramanuj, Fullwood, Melissa Jane, Tergaonkar, Vinay
Published 2023

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

by Zhu, Guanhua, Guo, Yu A., Ho, Danliang, Poon, Polly, Poh, Zhong Wee, Wong, Pui Mun, Gan, Anna, Chang, Mei Mei, Kleftogiannis, Dimitrios, Lau, Yi Ting, Tay, Brenda, Lim, Wan Jun, Chua, Clarinda, Tan, Tira J., Koo, Si-Lin, Chong, Dawn Q., Yap, Yoon Sim, Tan, Iain, Ng, Sarah, Skanderup, Anders J.
Published 2022

Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia

by Fukawa, Tomoya, Ong, Pauline, Li, Zhimei, Chen, Shuwen, Mak, Shi Ya, Kanayama, Hiro-omi, Mohan, Rosmin Elsa, Wang, Ruiqi Rachel, Chua, Benjamin Yan-Jiang, Chua, Jason Min-Wen, Tan, Elwin Jun-Hao, Huang, Dan, Qian, Chao-Nan, Lim, Wan Jun, Lai, Jiunn Herng, Chua, Clarinda, Ong, Hock Soo, Tan, Ker-Kan, Ho, Ying Swan, Tan, Iain Beehuat, Teh, Bin Tean, Ng, Shyh-Chang
Published 2017

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

by Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Published 2019

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein (vol 10, 2484, 2019)

by Thura, Min, Al-Aidaroos, Abdul Qader, Gupta, Abhishek, Chee, Cheng Ean, Lee, Soo Chin, Hui, Kam Man, Li, Jie, Guan, Yeoh Khay, Yong, Wei Peng, So, Jimmy, Chng, Wee Joo, Ng, Chin Hin, Zhou, Jianbiao, Wang, Ling Zhi, Yuen, John Shyi Peng, Ho, Henry Sun Sien, Yi, Sim Mei, Chiong, Edmund, Choo, Su Pin, Ngeow, Joanne, Ng, Matthew Chau Hsien, Chua, Clarinda, Yeo, Eugene Shen Ann, Tan, Iain Bee Huat, Sng, Joel Xuan En, Tan, Nicholas Yan Zhi, Thiery, Jean Paul, Goh, Boon Cher, Zeng, Qi
Published 2021