Loop diuretics are open-channel blockers of the cystic fibrosis transmembrane conductance regulator with distinct kinetics

بواسطة Min Ju, Toby S. Scott-Ward, Jia Liu, Pissared Khuituan, Hongyu Li, Zhiwei Cai, Stephen M. Husbands, David N. Sheppard
منشور في 2018

Parathyroid hormone increases CFTR expression and function in Caco-2 intestinal epithelial cells

بواسطة Walailak Jantarajit, Kannikar Wongdee, Kornkamon Lertsuwan, Jarinthorn Teerapornpuntakit, Ratchaneevan Aeimlapa, Jirawan Thongbunchoo, Bartholomew S.J. Harvey, David N. Sheppard, Narattaphol Charoenphandhu
منشور في 2020

Carbon monoxide-releasing molecules inhibit the cystic fibrosis transmembrane conductance regulator Cl-channel

بواسطة Mayuree Rodrat, Walailak Jantarajit, Demi R.S. Ng, Bartholomew S.J. Harvey, Jia Liu, William J. Wilkinson, Narattaphol Charoenphandhu, David N. Sheppard
منشور في 2021

A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR

بواسطة Jia Liu, Allison P. Berg, Yiting Wang, Walailak Jantarajit, Katy J. Sutcliffe, Edward B. Stevens, Lishuang Cao, Marko J. Pregel, David N. Sheppard
منشور في 2022

Impact of the F508del mutation on ovine CFTR, a Cl<sup>-</sup> channel with enhanced conductance and ATP-dependent gating

بواسطة Zhiwei Cai, Timea Palmai-Pallag, Pissared Khuituan, Michael J. Mutolo, Clément Boinot, Beihui Liu, Toby S. Scott-Ward, Isabelle Callebaut, Ann Harris, David N. Sheppard
منشور في 2018

Correlating genotype with phenotype using CFTR-mediated whole-cell Cl⁻ currents in human nasal epithelial cells

بواسطة Sabrina Noel, Nathalie Servel, Aurélie Hatton, Anita Golec, Mayuree Rodrat, Demi R.S. Ng, Hongyu Li, Iwona Pranke, Alexandre Hinzpeter, Aleksander Edelman, David N. Sheppard, Isabelle Sermet-Gaudelus
منشور في 2022

Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting smal...

بواسطة Jia Liu, Hermann Bihler, Carlos M. Farinha, Nikhil T. Awatade, Ana M. Romão, Dayna Mercadante, Yi Cheng, Isaac Musisi, Walailak Jantarajit, Yiting Wang, Zhiwei Cai, Margarida D. Amaral, Martin Mense, David N. Sheppard
منشور في 2019