Multifactorial Prediction of Anthracycline-Induced Cardiotoxicity in Childhood Cancer: 10 Years of Active Surveillance and Pharmacogenomics Studies at the Canadian Pharmacogenomics...

by Aminkeng, Folefac, Rassekh, Shahrad, Bhavsar, Amit, Luo, Hao, Wright, Galen, Drogemoller, Britt, Rieder, Michael, Hayden, Michael, Ross, Colin, Carleton, Bruce
Published 2022

Palmitoylation of caspase-6 by HIP14 regulates its activation

by Skotte, Niels H, Sanders, Shaun S, Singaraja, Roshni R, Ehrnhoefer, Dagmar E, Vaid, Kuljeet, Qiu, Xiaofan, Kannan, Srinivasaragavan, Verma, Chandra, Hayden, Michael R
Published 2024

Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease

by Garcia-Miralles, Marta, Ooi, Jolene, Bardile, Costanza Ferrari, Tan, Liang Juin, George, Maya, Drum, Chester L, Lin, Rachel Yanping, Hayden, Michael R, Pouladi, Mahmoud A
Published 2022

Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer

by Aminkeng, Folefac, Ross, Colin JD, Rassekh, Shahrad R, Rieder, Michael J, Bhavsar, Amit P, Sanatani, Shubhayan, Bernstein, Daniel, Hayden, Michael R, Amstutz, Ursula, Carleton, Bruce C
Published 2022

Predicting Anthracycline-induced Cardiotoxicity in Children - Genome-Wide Association Study

by Aminkeng, Folefac, Ross, Colin JD, Rassekh, Rod S, Brunham, Liam R, Weissman, Cory, Dube, Marie-Pierre, Visscher, Henk, Rieder, Michael J, Carleton, Bruce C, Hayden, Michael R
Published 2022

Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity

by Aminkeng, Folefac, Ross, Colin JD, Rassekh, Shahrad R, Hwang, Soomi, Rieder, Michael J, Bhavsar, Amit P, Smith, Anne, Sanatani, Shubhayan, Gelmon, Karen A, Bernstein, Daniel, Hayden, Michael R, Amstutz, Ursula, Carleton, Bruce C
Published 2022

Genetic Variation in SLC16A5 Confers Protection from Cisplatin-Induced Ototoxicity in Adult Testicular Cancer Patients

by Drogemoller, Britt, Monzon, Jose, Bhavsar, Amit, Borrie, Adrienne, Brooks, Beth, Wright, Galen, Liu, Geoffrey, Fadhel, Ehab, Renouf, Daniel, Kollmannsberger, Christian, Bedard, Philippe, Aminkeng, Folefac, Hildebrand, Claudette, Gunaretnam, Erandika, Critchley, Carol, Chen, Zhou, Brunham, Liam, Hayden, Michael, Ross, Colin, Gelmon, Karen, Carleton, Bruce
Published 2022

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease

by Bardile, Costanza Ferrari, Garcia-Miralles, Marta, Caron, Nicholas S., Rayan, Nirmala Arul, Langley, Sarah Raye, Harmston, Nathan, Rondelli, Ana Maria, Teo, Roy Tang Yi, Waltl, Sabine, Anderson, Lisa M., Bae, Han-Gyu, Jung, Sangyong, Williams, Anna, Prabhakar, Shyam, Petretto, Enrico, Hayden, Michael R., Pouladi, Mahmoud A.
Published 2020

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

by Aminkeng, Folefac, Bhavsar, Amit P, Visscher, Henk, Rassekh, Shahrad R, Li, Yuling, Lee, Jong W, Brunham, Liam R, Caron, Huib N, van Dalen, Elvira C, Kremer, Leontien C, van der Pal, Helena J, Amstutz, Ursula, Rieder, Michael J, Bernstein, Daniel, Carleton, Bruce C, Hayden, Michael R, Ross, Colin JD
Published 2022

Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer

by Drogemoller, Britt I, Monzon, Jose G, Bhavsar, Amit P, Borrie, Adrienne E, Brooks, Beth, Wright, Galen EB, Liu, Geoffrey, Renouf, Daniel J, Kollmannsberger, Christian K, Bedard, Philippe L, Aminkeng, Folefac, Amstutz, Ursula, Hildebrand, Claudette A, Gunaretnam, Erandika P, Critchley, Carol, Chen, Zhuo, Brunham, Liam R, Hayden, Michael R, Ross, Colin JD, Gelmon, Karen A, Carleton, Bruce C
Published 2022

ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels

by Trigueros-Motos, Laia, van Capelleveen, Julian C, Torta, Federico, Castano, David, Zhang, Lin-Hua, Chai, Ee Chu, Kang, Martin, Dimova, Lidiya G, Schimmel, Alinda WM, Tietjen, Ian, Radomski, Chris, Tan, Liang Juin, Thiam, Chung Hwee, Narayanaswamy, Pradeep, Wu, Daniel Heqing, Dorninger, Fabian, Yakala, Gopala Krishna, Barhdadi, Amina, Angeli, Veronique, Dube, Marie-Pierre, Berger, Johannes, Dallinga-Thie, Geesje M, Tietge, Uwe JF, Wenk, Markus R, Hayden, Michael R, Hovingh, G Kees, Singaraja, Roshni R
Published 2020

Fundamental relations for the velocity dispersion of stars in the Milky Way

by Sharma, Sanjib, Hayden, Michael R., Bland-Hawthorn, Joss, Stello, Dennis, Buder, Sven, Zinn, Joel C., Kallinger, Thomas, Asplund, Martin, De Silva, Gayandhi M., D'Orazi, Valentina, Freeman, Ken, Kos, Janez, Lewis, Geraint F., Lin, Jane, Lind, Karin, Martell, Sarah, Simpson, Jeffrey D., Wittenmyer, Rob A., Zucker, Daniel B., Zwitter, Tomaz, Chen, Boquan, Cotar, Klemen, Esdaile, James, Hon, Marc, Horner, Jonathan, Huber, Daniel, Kafle, Prajwal R., Khanna, Shourya, Ting, Yuan-Sen, Nataf, David M., Nordlander, Thomas, Mohd Saadon, Mohd Hafiz, Tepper-Garcia, Thor, Tinney, C. G., Traven, Gregor, Watson, Fred, Wright, Duncan, Wyse, Rosemary F. G.
Published 2021

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes

by Wright, Galen EB, Amstutz, Ursula, Drogemoller, Britt, Shih, Joanne, Rassekh, Shahrad R, Hayden, Michael R, Carleton, Bruce C, Ross, Colin JD, Carleton, Bruce, Ross, Colin, Rassekh, Shahrad, Visscher, Henk, Aminkeng, Folefac, Wright, Galen, Drogemoller, Britt, Higginson, Michelle, Massah, Nasim, Miao, Fudan, Bhavsar, Amit, Lee, Jong, Bendyshe-Walton, Tessa, Tanoshima, Reo, Johnson, David, Zhuwaki, Carnation, Honcharik, Nick, Jong, Geert't, Israels, Sara, Staub, Michelle, Rieder, Michael, Faught, Lauren, Ito, Shinya, Nathan, Paul, Karande, Smita, Vaillancourt, Regis, Johnston, Donna, Nguyen, Kimmy, Bussieres, Jean-Francois, Lebel, Denis, Jean-Louis, Jennifer
Published 2022