Jason McLellan
Jason S. McLellan is a structural biologist, professor in the Department of Molecular Biosciences and Robert A. Welch Chair in Chemistry at The University of Texas at Austin who specializes in understanding the structure and function of viral proteins, including those of coronaviruses. His research focuses on applying structural information to the rational design of vaccines and other therapies for viruses, including SARS-CoV-2, the novel coronavirus that causes COVID-19, and respiratory syncytial virus (RSV). McLellan and his team collaborated with researchers at the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which biotechnology company Moderna used as the basis for the vaccine mRNA-1273, the first COVID-19 vaccine candidate to enter phase I clinical trials in the U.S. At least three other vaccines use this modified spike protein: those from Pfizer and BioNTech; Johnson & Johnson and Janssen Pharmaceuticals; and Novavax. Provided by Wikipedia
1
by Anh Duc Dang, Thiem Dinh Vu, Ha Hai Vu, Van Thanh Ta, Anh Thi Van Pham, Mai Thi Ngoc Dang, Be Van Le, Thai Huu Duong, Duoc Van Nguyen, Saranath Lawpoolsri, Pailinrut Chinwangso, Jason S. McLellan, Ching Lin Hsieh, Adolfo Garcia-Sastre, Peter Palese, Weina Sun, Jose L. Martinez, Irene Gonzalez-Dominguez, Stefan Slamanig, Juan Manuel Carreño, Johnstone Tcheou, Florian Krammer, Ariel Raskin, Huong Minh Vu, Thang Cong Tran, Huong Mai Nguyen, Laina D. Mercer, Rama Raghunandan, Manjari Lal, Jessica A. White, Richard Hjorth, Bruce L. Innis, Rami Scharf
Published 2022
Get full textPublished 2022
Article
2
by Hua Xin Liao, Mattia Bonsignori, S. Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M. Anthony Moody, Daniel M. Kozink, Kwan Ki Hwang, Xi Chen, Chun Yen Tsao, Pinghuang Liu, Xiaozhi Lu, Robert J. Parks, David C. Montefiori, Guido Ferrari, Justin Pollara, Mangala Rao, Kristina K. Peachman, Sampa Santra, Norman L. Letvin, Nicos Karasavvas, Zhi Yong Yang, Kaifan Dai, Marie Pancera, Jason Gorman, Kevin Wiehe, Nathan I. Nicely, Supachai Rerks-Ngarm, Sorachai Nitayaphan, Jaranit Kaewkungwal, Punnee Pitisuttithum, James Tartaglia, Faruk Sinangil, Jerome H. Kim, Nelson L. Michael, Thomas B. Kepler, Peter D. Kwong, John R. Mascola, Gary J. Nabel, Abraham Pinter, Susan Zolla-Pazner, Barton F. Haynes
Published 2018
Get full textPublished 2018
Article