Labdane diterpenes from the aerial parts of curcuma comosa enhance fetal hemoglobin production in an erythroid cell line

by Ratchanaporn Chokchaisiri, Nattawara Chaneiam, Saovaros Svasti, Suthat Fucharoen, Jim Vadolas, Apichart Suksamrarn
Published 2018

Imbalanced globin chain synthesis determines erythroid cell pathology in thalassemic mice

by Kanitta Srinoun, Saovaros Svasti, Worrakavee Chumworathayee, Jim Vadolas, Phantip Vattanaviboon, Suthat Fucharoen, Pranee Winichagoon Fucharoen
Published 2018

Heart rate variability in β-thalassemic mice

by Tanat Incharoen, Chontida Thephinlap, Somdej Srichairatanakool, Siriporn Chattipakorn, Pranee Winichagoon, Suthat Fucharoen, Jim Vadolas, Nipon Chattipakorn
Published 2018

Heart rate variability in β-thalassemic mice

by Tanat Incharoen, Chontida Thephinlap, Somdej Srichairatanakool, Siriporn Chattipakorn, Pranee Winichagoon, Suthat Fucharoen, Jim Vadolas, Nipon Chattipakorn
Published 2018

Increased ferritin levels in non-transfusion-dependent β°-thalassaemia/HbE are associated with reduced CXCR2 expression and neutrophil migration

by Chayada Thiengtavor, Sirikwan Siriworadetkun, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Saovaros Svasti, Pornthip Chaichompoo
Published 2020

Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE

by Rattanawan Thubthed, Sirikwan Siriworadetkun, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Saovaros Svasti, Pornthip Chaichompoo
Published 2022

Transgene copy number-dependent rescue of murine β-globin knockout mice carrying a 183 kb human β-globin BAC genomic fragment

by Jim Vadolas, Hady Wardan, Marco Bosmans, Faten Zaibak, Duangporn Jamsai, Lucille Voullaire, Robert Williamson, Panos A. Ioannou
Published 2018

A reduced curcuminoid analog as a novel inducer of fetal hemoglobin

by Nattawara Chaneiam, Chatchawan Changtam, Thongperm Mungkongdee, Umaporn Suthatvoravut, Pranee Winichagoon, Jim Vadolas, Apichart Suksamrarn, Suthat Fucharoen, Saovaros Svasti
Published 2018

Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients

by Mayura Meerang, Jagadeesan Nair, Pornpan Sirankapracha, Chonthida Thephinlap, Somdet Srichairatanakool, Khelifa Arab, Ruchaneekorn Kalpravidh, Jim Vadolas, Suthat Fucharoen, Helmut Bartsch
Published 2018

Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients

by Mayura Meerang, Jagadeesan Nair, Pornpan Sirankapracha, Chonthida Thephinlap, Somdet Srichairatanakool, Khelifa Arab, Ruchaneekorn Kalpravidh, Jim Vadolas, Suthat Fucharoen, Helmut Bartsch
Published 2018

Hepcidin and 1,25(OH)<inf>2</inf>D<inf>3</inf>effectively restore Ca²⁺transport in β-thalassemic mice: Reciprocal phenomenon of Fe²⁺and Ca²⁺absorpt...

by Kamonshanok Kraidith, Saovaros Svasti, Jarinthorn Teerapornpuntakit, Jim Vadolas, Rattana Chaimana, Sarawut Lapmanee, Panan Suntornsaratoon, Nateetip Krishnamra, Suthat Fucharoen, Narattaphol Charoenphandhu
Published 2018

Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at ^Gγ-globin gene promoter

by Khanita Nuamsee, Thipphawan Chuprajob, Wachirachai Pabuprapap, Pornrutsami Jintaridth, Thongperm Munkongdee, Phatchariya Phannasil, Jim Vadolas, Pornthip Chaichompoo, Apichart Suksamrarn, Saovaros Svasti
Published 2022

Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients

by Mayura Meerang, Jagadeesan Nair, Pornpan Sirankapracha, Chonthida Thephinlap, Somdet Srichairatanakool, Khelifa Arab, Ruchaneekorn Kalpravidh, Jim Vadolas, Suthat Fucharoen, Helmut Bartsch
Published 2018

Elevated levels of circulating monocytic myeloid derived suppressor cells in splenectomised β-thalassaemia/HbE patients

by Sirikwan Siriworadetkun, Rattanawan Thubthed, Chayada Thiengtavor, Kittiphong Paiboonsukwong, Archrob Khuhapinant, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Saovaros Svasti, Pornthip Chaichompoo
Published 2020

A humanized mouse model for a common β⁰-thalassemia mutation

by Duangporn Jamsai, Faten Zaibak, Wantana Khongnium, Jim Vadolas, Lucille Voullaire, Kerry J. Fowler, Sophie Gazeas, Suthat Fucharoen, Robert Williamson, Panayiotis A. Ioannou
Published 2018

Effect of human β-globin bacterial artificial chromosome transgenesis on embryo cryopreservation in mouse models

by Duangjai Boonkusol, Andras Dinnyes, Tassanee Faisaikarm, Parisatcha Sangsuwan, Nathnapith Pratipnatalang, Mayurachat Sa-Ardrit, Kulnasan Saikhun, Saovaros Svasti, Jim Vadolas, Pranee Winichagoon, Suthat Fucharoen, Yindee Kitiyanant
Published 2018

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

by Bradley McColl, Betty R. Kao, Preeyachan Lourthai, Kasey Chan, Hady Wardan, Mark Roosjen, Orane Delagneau, Linden J. Gearing, Marnie E. Blewitt, Saovaros Svasti, Suthat Fucharoen, Jim Vadolas
Published 2018

Reduced PU.1 expression underlies aberrant neutrophil maturation and function in b-Thalassemia mice and patients

by Panjaree Siwaponanan, Jurre Ynze Siegers, Razi Ghazali, Thian Ng, Bradley Mccoll, Garrett Zhen Wei Ng, Philip Sutton, Nancy Wang, Isabelle Ooi, Chayada Thiengtavor, Suthat Fucharoen, Pornthip Chaichompoo, Saovaros Svasti, Odilia Wijburg, Jim Vadolas
Published 2018

Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia

by Tiwaporn Nualkaew, Karine Sii-Felice, Marie Giorgi, Bradley McColl, Julie Gouzil, Astrid Glaser, Hsiao P.J. Voon, Hsin Y. Tee, George Grigoriadis, Saovaros Svasti, Suthat Fucharoen, Suradej Hongeng, Philippe Leboulch, Emmanuel Payen, Jim Vadolas
Published 2022