Hemoglobin disorders: lentiviral gene therapy in the starting blocks to enter clinical practice

by Karine Sii-Felice, Marie Giorgi, Philippe Leboulch, Emmanuel Payen
Published 2019

The integrity of the FOG-2 LXCXE pRb-binding motif is required for small intestine homeostasis

by Olivier Goupille, Zahra Kadri, Amandine Langelé, Sophie Luccantoni, Cécile Badoual, Philippe Leboulch, Stany Chrétien
Published 2020

BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7

by Olivier Goupille, Tipparat Penglong, Carine Lefèvre, Marine Granger, Zahra Kadri, Suthat Fucharoen, Leila Maouche-Chrétien, Philippe Leboulch, Stany Chrétien
Published 2018

Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis

by Olivier Goupille, Tipparat Penglong, Zahra Kadri, Marine Granger-Locatelli, Suthat Fucharoen, Leila Maouche-Chrétien, Stéphane Prost, Philippe Leboulch, Stany Chrétien
Published 2018

Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis

by Zahra Kadri, Carine Lefevre, Olivier Goupille, Tipparat Penglong, Marine Granger-Locatelli, Suthat Fucharoen, Leila Maouche-Chretien, Philippe Leboulch, Stany Chretien
Published 2018

Enhanced Transduction of Macaca fascicularis Hematopoietic Cells with Chimeric Lentiviral Vectors

by Karine Sii-Felice, Javier Castillo Padilla, Francis Relouzat, Joëlle Cheuzeville, Siriporn Tantawet, Leïla Maouche, Roger Le Grand, Philippe Leboulch, Emmanuel Payen
Published 2020

The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis

by Olivier Goupille, Tipparat Penglong, Zahra Kadri, Marine Granger-Locatelli, Raphaël Denis, Serge Luquet, Cécile Badoual, Suthat Fucharoen, Leila Maouche-Chrétien, Philippe Leboulch, Stany Chrétien
Published 2018

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β^a(T87Q)-Globin Gene

by Olivier Negre, Anne Virginie Eggimann, Yves Beuzard, Jean Antoine Ribeil, Philippe Bourget, Suparerk Borwornpinyo, Suradej Hongeng, Salima Hacein-Bey, Marina Cavazzana, Philippe Leboulch, Emmanuel Payen
Published 2018

Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia

by Tiwaporn Nualkaew, Karine Sii-Felice, Marie Giorgi, Bradley McColl, Julie Gouzil, Astrid Glaser, Hsiao P.J. Voon, Hsin Y. Tee, George Grigoriadis, Saovaros Svasti, Suthat Fucharoen, Suradej Hongeng, Philippe Leboulch, Emmanuel Payen, Jim Vadolas
Published 2022

Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient

by Alisa Tubsuwan, Soumeya Abed, Annette Deichmann, Melanie D. Kardel, Cynthia Bartholomä, Alice Cheung, Olivier Negre, Zahra Kadri, Suthat Fucharoen, Christof Von Kalle, Emmanuel Payen, Stany Chrétien, Manfred Schmidt, Connie J. Eaves, Philippe Leboulch, Leïla Maouche-Chrétien
Published 2018

Pioglitazone together with imatinib in chronic myeloid leukemia: A proof of concept study

by Philippe Rousselot, Stéphane Prost, Joelle Guilhot, Lydia Roy, Gabriel Etienne, Laurence Legros, Aude Charbonnier, Valérie Coiteux, Pascale Cony-Makhoul, Francoise Huguet, Emilie Cayssials, Jean Michel Cayuela, Francis Relouzat, Marc Delord, Heriberto Bruzzoni-Giovanelli, Laure Morisset, François Xavier Mahon, François Guilhot, Philippe Leboulch
Published 2018

Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice

by Soumeya Abed, Alisa Tubsuwan, Porntip Chaichompoo, In Hyun Park, Alice Pailleret, Aïssa Benyoucef, Lucie Tosca, Edouard De Dreuzy, Anais Paulard, Marine Granger-Locatelli, Francis Relouzat, Stéphane Prost, Gerard Tachdjian, Suthat Fucharoen, George Q. Daley, Emmanuel Payen, Stany Chrétien, Philippe Leboulch, Leïla Maouche-Chrétien
Published 2018