Mechanism of action of membrane-active marine natural product theonellamide A

by Espiritu, Rafael Atillo, Matsumori, Nobuaki, Kinoshita, Masanao, Murata, Michio, Nishimura, Shinichi, Kakeya, Hideaki, Matsunaga, Shigeki, Yoshida, Minoru
Published 2013

Marine sponge cyclic peptide theonellamide A disrupts lipid bilayer integrity without forming distinct membrane pores

by Espiritu, Rafael Atillo, Cornelio, Kimberly, Kinoshita, Masanao, Matsumori, Nobuaki, Murata, Michio, Nishimura, Shinichi, Kakeya, Hideaki, Yoshida, Minoru, Matsunaga, Shigeki
Published 2016

Sterol-dependent membrane association of the marine sponge-derived bicyclic peptide Theonellamide A as examined by¹H NMR

by Cornelio, Kimberly, Espiritu, Rafael Atillo, Todokoro, Yasuto, Hanashima, Shinya, Kinoshita, Masanao, Matsumori, Nobuaki, Murata, Michio, Nishimura, Shinichi, Kakeya, Hideaki, Yoshida, Minoru, Matsunaga, Shigeki
Published 2016

Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated stero...

by Cornelio, Kimberly, Espiritu, Rafael Atillo, Hanashima, Shinya, Todokoro, Yasuto, Malabed, Raymond, Kinoshita, Masanao, Matsumori, Nobuaki, Murata, Michio, Nishimura, Shinichi, Kakeya, Hideaki, Yoshida, Minoru, Matsunaga, Shigeki
Published 2019