RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade

by Oei, Vincent, Chuang, Linda Shyue Huey, Matsuo, Junichi, Srivastava, Supriya, Teh, Ming, Ito, Yoshiaki
Published 2024

RUNX3 in Stem Cell and Cancer Biology

by Chuang, Linda Shyue Huey, Matsuo, Junichi, Douchi, Daisuke, Mawan, Nur Astiana Bte, Ito, Yoshiaki
Published 2023

A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells

by Matsuo, Junichi, Mon, Naing Naing, Douchi, Daisuke, Yamamura, Akihiro, Kulkarni, Madhura, Heng, Dede Liana, Chen, Sabirah, Nuttonmanit, Napat, Li, Ying, Yang, Henry, Lee, May Yin, Tam, Wai Leong, Osato, Motomi, Chuang, Linda Shyue Huey, Ito, Yoshiaki
Published 2022

Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer

by Suda, Kazuto, Okabe, Atsushi, Matsuo, Junichi, Chuang, Linda Shyue Huey, Li, Ying, Jangphattananont, Nawaphat, Mon, Naing Naing, Myint, Khine Nyein, Yamamura, Akihiro, So, Jimmy Bok-Yan, Voon, Dominic Chih-Cheng, Yang, Henry, Yeoh, Khay Guan, Kaneda, Atsushi, Ito, Yoshiaki
Published 2024

DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia

by Krishnan, Vaidehi, Lim, Debbie Xiu En, Hoang, Phuong Mai, Srivastava, Supriya, Matsuo, Junichi, Huang, Kie Kyon, Zhu, Feng, Ho, Khek Yu, So, Jimmy Bok Yan, Khor, Christopher, Tsao, Stephen, Teh, Ming, Fock, Kwong Ming, Ang, Tiing Leong, Jeyasekharan, Anand D, Tan, Patrick, Yeoh, Khay-Guan, Ito, Yoshiaki
Published 2020

Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer

by Myint, Khine, Chuang, Linda Shyue Huey, Teh, Yu Xuan, Mawan, Nur Astiana, Shi, Edward Jizhong, Mok, Michelle Meng Huang, Nuttonmanit, Napat, Matsuo, Junichi, Li, Ying, Yang, Henry, Okabe, Atsushi, Kaneda, Atsushi, Osato, Motomi, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Ito, Yoshiaki
Published 2023

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach

by Douchi, Daisuke, Yamamura, Akihiro, Matsuo, Junichi, Lee, Jung-Won, Nuttonmanit, Napat, Lim, Yi Hui Melissa, Suda, Kazuto, Shimura, Mitsuhiro, Chen, Sabirah, Pang, ShuChin, Kohu, Kazuyoshi, Kaneko, Mari, Kiyonari, Hiroshi, Kaneda, Atsushi, Yoshida, Hideyuki, Taniuchi, Ichiro, Osato, Motomi, Yang, Henry, Unno, Michiaki, So, Jimmy Bok-Yan, Yeoh, Khay Guan, Chuang, Linda Shyue Huey, Bae, Suk-Chul, Ito, Yoshiaki
Published 2023

Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair

by Matsuo, Junichi, Douchi, Daisuke, Myint, Khine, Mon, Naing Naing, Yamamura, Akihiro, Kohu, Kazuyoshi, Heng, Dede Liana, Chen, Sabirah, Mawan, Nur Astiana, Nuttonmanit, Napat, Li, Ying, Srivastava, Supriya, Ho, Shamaine Wei Ting, Lee, Nicole Yee Shin, Lee, Hong Kai, Adachi, Makoto, Tamura, Atsushi, Chen, Jinmiao, Yang, Henry, Ming Teh, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Chuang, Linda Shyue Huey, Tsukita, Sachiko, Ito, Yoshiaki
Published 2021