The RUNX1 Enhancer Element eR1: A Versatile Marker for Adult Stem Cells

by Chuang, Linda Shyue Huey, Osato, Motomi, Ito, Yoshiaki
Published 2021

Systematic Review of Normal Subjects Harbouring BCR-ABL1 Fusion Gene

by Kuan, Jew-Win, Anselm, Su Ting, Leong, Chooi Fun, Osato, Motomi, Sashida, Goro
Published 2019

Lineage-specific RUNX2 super-enhancer activates MYC via a chromosomal translocation and promotes the BPDCN

by Kubota, Sho, Umezu, Tomohiro, Iwama, Atsushi, Ohyashiki, Kazuma, Osato, Motomi, Sashida, Goro
Published 2019

Runx family genes in a cartilaginous Fish, the elephant Shark (Callorhinchus milii)

by Nah, Giselle Sek Suan, Lim, Zhi Wei, Tay, Boon-Hui, Osato, Motomi, Venkatesh, Byrappa
Published 2014

Low prevalence of the BCR–ABL1 fusion gene in a normal population in southern Sarawak

by Anselm, Su Ting, Lim, Isabel Fong, Lela, Binti Suut, Jew, Win Kuan, Siow, Phing Tay, Kubota, Sho, Osato, Motomi, Sashida, Goro
Published 2019

Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines

by Hosoi, Hiroki, Niibori-Nambu, Akiko, Nah, Giselle Sek Suan, Bahirvani, Avinash Govind, Mok, Michelle Meng Huang, Sanda, Takaomi, Kumar, Alan Prem, Tenen, Daniel G, Ito, Yoshiaki, Sonoki, Takashi, Osato, Motomi
Published 2023

ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function

by Zhou, Qiling, Yu, Miao, Tirado-Magallanes, Roberto, Li, Bin, Kong, Lingshi, Guo, Mingrui, Tan, Zi Hui, Lee, Sanghoon, Chai, Li, Numata, Akihiko, Benoukraf, Touati, Fullwood, Melissa Jane, Osato, Motomi, Ren, Bing, Tenen, Daniel G.
Published 2022

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.

by Zhou, Jianbiao, Yiying Quah, Jessie, Ng, Yvonne, Chooi, Jing-Yuan, Hui-Min Toh, Sabrina, Lin, Baohong, Zea Tan, Tuan, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, Lisa AG, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo
Published 2022

A Runx1-enhancer Element eR1 Identified Lineage Restricted Mammary Luminal Stem Cells

by Matsuo, Junichi, Mon, Naing Naing, Douchi, Daisuke, Yamamura, Akihiro, Kulkarni, Madhura, Heng, Dede Liana, Chen, Sabirah, Nuttonmanit, Napat, Li, Ying, Yang, Henry, Lee, May Yin, Tam, Wai Leong, Osato, Motomi, Chuang, Linda Shyue Huey, Ito, Yoshiaki
Published 2022

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML

by Zhou, Jianbiao, Chan, Zit-Liang, Bi, Chonglei, Lu, Xiao, Chong, Phyllis SY, Chooi, Jing-Yuan, Cheong, Lip-Lee, Liu, Shaw-Cheng, Ching, Ying Qing, Zhou, Yafeng, Osato, Motomi, Tan, Tuan Zea, Ng, Chin Hin, Ng, Siok-Bian, Wang, Shi, Zeng, Qi, Chng, Wee-Joo
Published 2021

Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer

by Myint, Khine, Chuang, Linda Shyue Huey, Teh, Yu Xuan, Mawan, Nur Astiana, Shi, Edward Jizhong, Mok, Michelle Meng Huang, Nuttonmanit, Napat, Matsuo, Junichi, Li, Ying, Yang, Henry, Okabe, Atsushi, Kaneda, Atsushi, Osato, Motomi, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Ito, Yoshiaki
Published 2023

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth

by Zhang, Ying, Chen, Kaijing, Tang, Seng Chuan, Cai, Yichao, Nambu, Akiko, See, Yi Xiang, Fu, Chaoyu, Raju, Anandhkumar, Lebeau, Benjamin, Ling, Zixun, Chan, Jia Jia, Tay, Yvonne, Mutwil, Marek, Lakshmanan, Manikandan, Tucker-Kellogg, Greg, Chng, Wee Joo, Tenen, Daniel G, Osato, Motomi, Tergaonkar, Vinay, Fullwood, Melissa Jane
Published 2024

RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner

by Abdallah, Mohamed Gaber, Niibori-Nambu, Akiko, Morii, Mariko, Yokomizo, Takako, Yokomizo, Tomomasa, Ideue, Takako, Kubota, Sho, Teoh, Vania Swee Imm, Mok, Michelle Meng Huang, Wang, Chelsia Qiuxia, Omar, Abdellah Ali, Tokunaga, Kenji, Iwanaga, Eisaku, Matsuoka, Masao, Asou, Norio, Nakagata, Naomi, Araki, Kimi, AboElenin, Mabrouk, Madboly, Sayed Hamada, Sashida, Goro, Osato, Motomi
Published 2022

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach

by Douchi, Daisuke, Yamamura, Akihiro, Matsuo, Junichi, Lee, Jung-Won, Nuttonmanit, Napat, Lim, Yi Hui Melissa, Suda, Kazuto, Shimura, Mitsuhiro, Chen, Sabirah, Pang, ShuChin, Kohu, Kazuyoshi, Kaneko, Mari, Kiyonari, Hiroshi, Kaneda, Atsushi, Yoshida, Hideyuki, Taniuchi, Ichiro, Osato, Motomi, Yang, Henry, Unno, Michiaki, So, Jimmy Bok-Yan, Yeoh, Khay Guan, Chuang, Linda Shyue Huey, Bae, Suk-Chul, Ito, Yoshiaki
Published 2023

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

by Guo, Mingrui, Chan, Tim Hon Man, Zhou, Qiling, An, Omer, Li, Ying, Song, Yangyang, Tan, Zi Hui, Ng, Vanessa Hui En, Peramangalam, Philomina Sona, Tan, Zhi Qing, Cao, Xinang, Iwanaga, Eisaku, Matsuoka, Masao, Ooi, Melissa G. M., Jen, Wei Ying, Koh, Liang Piu, Chan, Esther, Tan, Lip Kun, Goh, Yufen, Wang, Wilson, Koh, Bryan T. H., Chun, Chan Ming, Fullwood, Melissa Jane, Chng, Wee Joo, Osato, Motomi, Pulikkan, John Anto, Yang, Henry, Chen, Leilei, Tenen, Daniel G.
Published 2023