Cell-free DNA promotes thrombin autolysis and generation of thrombin-derived C-terminal fragments

by Saravanan, Rathi, Choong, Yeu Khai, Lim, Chun Hwee, Lim, Li Ming, Petrlova, Jitka, Schmidtchen, Artur
Published 2021

Cell-Free DNA Promotes Thrombin Autolysis and Generation of Thrombin-Derived C-Terminal Fragments

by Saravanan, Rathi, Choong, Yeu Khai, Lim, Chun Hwee, Lim, Li Ming, Petrlova, Jitka, Schmidtchen, Artur
Published 2022

Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

by Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur
Published 2024

Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism

by Petrlova, Jitka, Hansen, Finja C., van der Plas, Mariena J. A., Huber, Roland G., Mörgelin, Matthias, Malmsten, Martin, Bond, Peter J., Schmidtchen, Artur
Published 2017

Proteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo

by Saravanan, Rathi, Adav, Sunil Shankar, Choong, Yeu Khai, van der Plas, Mariena J. A., Petrlova, Jitka, Kjellström, Sven, Sze, Siu Kwan, Schmidtchen, Artur
Published 2017

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides

by Saravanan, Rathi, Holdbrook, Daniel A, Petrlova, Jitka, Singh, Shalini, Berglund, Nils A, Choong, Yeu Khai, Kjellström, Sven, Bond, Peter J, Malmsten, Martin, Schmidtchen, Artur
Published 2018