Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...

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Bibliographic Details
Main Authors: Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2024
Subjects:
Engineering
Bacteriology
Immunology
Online Access:https://hdl.handle.net/10356/173914
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/173914

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