Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation
Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...
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Main Authors: | Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur |
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Other Authors: | School of Materials Science and Engineering |
Format: | Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/173914 |
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Institution: | Nanyang Technological University |
Language: | English |
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