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Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...

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Main Authors: Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur
其他作者: School of Materials Science and Engineering
格式: Article
語言:English
出版: 2024
主題:
Engineering
Bacteriology
Immunology
在線閱讀:https://hdl.handle.net/10356/173914
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機構: Nanyang Technological University
語言: English

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https://hdl.handle.net/10356/173914

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