Structural dynamics and in silico design of pyrazolopyran-based inhibitors against Plasmodium serine hydroxymethyltransferases

by Pitchayathida Mee-udorn, Bodee Nutho, Romchalee Chootrakool, Somchart Maenpuen, Ubolsree Leartsakulpanich, Penchit Chitnumsub, Thanyada Rungrotmongkol
Published 2022

A flap motif in human serine hydroxymethyltransferase is important for structural stabilization, ligand binding, and control of product release

by Sakunrat Ubonprasert, Juthamas Jaroensuk, Wichai Pornthanakasem, Nuntaporn Kamonsutthipaijit, Peerapong Wongpituk, Pitchayathida Mee-Udorn, Thanyada Rungrotmongkol, Onuma Ketchart, Penchit Chitnumsub, Ubolsree Leartsakulpanich, Pimchai Chaiyen, Somchart Maenpuen
Published 2020