A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

by Luukkainen A., Puan K.J., Yusof N., Lee B., Tan K.S., Liu J., Yan Y., Toppila-Salmi S., Renkonen R., Chow V.T., Rotzschke O., Wang Y.
Published 2020

Establishing criteria for human mesenchymal stem cell potency

by Samsonraj, R.M, Rai, B, Sathiyanathan, P, Puan, K.J, Rötzschke, O, Hui, J.H, Raghunath, M, Stanton, L.W, Nurcombe, V, Cool, S.M
Published 2020

V?2+ and ?/? T cells show divergent trajectories during human aging

by Ying Tan, C.T, Wistuba-Hamprecht, K, Xu, W, Zin Nyunt, M.S, Vasudev, A, Kwong Lee, B.T, Pawelec, G, Puan, K.J, Rotzschke, O, Ng, T.P, Larbi, A
Published 2020

Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39

by Melchiotti R., Puan K.J., Andiappan A.K., Poh T.Y., Starke M., Zhuang L., Petsch K., Lai T.S., Chew F.T., Larbi A., Wang D.Y., Poidinger M., Rotzschke O.
Published 2018

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation

by Kumar, D., Lee, B., Puan, K.J., Lee, W., Luis, B.S., Yusof, N., Andiappan, A.K., Del Rosario, R., Poschmann, J., Kumar, P., DeLibero, G., Singhal, A., Prabhakar, S., De Yun, W., Poidinger, M., Rötzschke, O.
Published 2021

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

by Andiappan, A.K, Melchiotti, R, Poh, T.Y, Nah, M, Puan, K.J, Vigano, E, Haase, D, Yusof, N, San Luis, B, Lum, J, Kumar, D, Foo, S, Zhuang, L, Vasudev, A, Irwanto, A, Lee, B, Nardin, A, Liu, H, Zhang, F, Connolly, J, Liu, J, Mortellaro, A, Wang, D.Y, Poidinger, M, Larbi, A, Zolezzi, F, Rotzschke, O
Published 2020

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

by Carissimo, G., Xu, W., Kwok, I., Abdad, M.Y., Chan, Y.-H., Fong, S.-W., Puan, K.J., Lee, C.Y.-P., Yeo, N.K.-W., Amrun, S.N., Chee, R.S.-L., How, W., Chan, S., Fan, B.E., Andiappan, A.K., Lee, B., Rötzschke, O., Young, B.E., Leo, Y.-S., Lye, D.C., Renia, L., Ng, L.G., Larbi, A., Ng, L.F.
Published 2021

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

by Kumar D., Puan K.J., Andiappan A.K., Lee B., Westerlaken G.H.A., Haase D., Melchiotti R., Li Z., Yusof N., Lum J., Koh G., Foo S., Yeong J., Alves A.C., Pekkanen J., Sun L.D., Irwanto A., Fairfax B.P., Naranbhai V., Common J.E.A., Tang M., Chuang C.K., Jarvelin M.-R., Knight J.C., Zhang X., Chew F.T., Prabhakar S., Jianjun L., Wang D.Y., Zolezzi F., Poidinger M., Lane E.B., Meyaard L., Rötzschke O.
Published 2020

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

by Puan, KJ, San Luis, B, Yusof, N, Kumar, D, Andiappan, AK, Lee, W, Cajic, S, Vuckovic, D, Chan, JD, Döllner, T, Hou, HW, Jiang, Y, Tian, C, Agee, M, Aslibekyan, S, Auton, A, Babalola, E, Bell, RK, Bielenberg, J, Bryc, K, Bullis, E, Cameron, B, Coker, D, Partida, GC, Dhamija, D, Das, S, Elson, SL, Filshtein, T, Fletez-Brant, K, Fontanillas, P, Freyman, W, Gandhi, PM, Heilbron, K, Hicks, B, Hinds, DA, Huber, KE, Jewett, EM, Kleinman, A, Kukar, K, Lane, V, Lin, KH, Lowe, M, Luff, MK, McCreight, JC, McIntyre, MH, McManus, KF, Micheletti, SJ, Moreno, ME, Mountain, JL, Mozaffari, SV, Nandakumar, P., Noblin, ES, O’Connell, J, Petrakovitz, AA, Poznik, GD, Schumacher, M, Shastri, AJ, Shelton, JF, Shi, J, Shringarpure, S, Tran, V, Tung, JY, Wang, X, Wang W, Weldon, CH, Wilton, P, Rapp, E, Poidinger, M, Wang, DY, Soranzo, N, Lee, B, Rötzschke, O
Published 2022