A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

by Zhou, J, Toh, S.H.-M, Chan, Z.-L, Quah, J.Y, Chooi, J.-Y, Tan, T.Z, Chong, P.S.Y, Zeng, Q, Chng, W.-J
Published 2020

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

by Zhou, J, Bi, C, Ching, Y.Q, Chooi, J.-Y, Lu, X, Quah, J.Y, Toh, S.H.-M, Chan, Z.-L, Tan, T.Z, Chong, P.S, Chng, W.-J
Published 2020

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia

by Zhou, J., Quah, J.Y., Ng, Y., Chooi, J.-Y., Toh, S.H.-M., Lin, B., Tan, T.Z., Hosoi, H., Osato, M., Seet, Q., Lisa Ooi, A.G., Lindmark, B., McHale, M., Chng, W.-J.
Published 2021