Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound's edge with inflammasome activation, keratinocyte extrusion and epidermal detachment

by Ku, Joanne Wei Kay, Marsh, Supatra Tharinee, Nai, Mui Hoon, Robinson, Kim Samirah, Teo, Daniel Eng Thiam, Zhong, Franklin Lei, Brown, Katherine A., Lim, Thiam Chye, Lim, Chwee Teck, Gan, Yunn-Hwen
Published 2023

Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis

by Robinson, Kim Samirah, Toh, Gee Ann, Muhammad Jasrie Firdaus, Tham, Khek Chian, Rozario, Pritisha, Lim, Chrissie K., Toh, Ying Xiu, Lau, Zhi Heng, Binder, Sophie Charlotte, Mayer, Jacob, Bonnard, Carine, Schmidt, Florian I., Common, John E. A., Zhong, Franklin
Published 2023

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption

by Pinilla, Miriam, Mazars, Raoul, Vergé, Romain, Gorse, Leana, Paradis, Margaux, Suire, Bastien, Santoni, Karin, Robinson, Kim Samirah, Toh, Gee Ann, Prouvensier, Laure, Leon-Icaza, Stephen Adonai, Hessel, Audrey, Péricat, David, Murris, Marlène, Guet-Revillet, Hélène, Henras, Anthony, Buyck, Julien, Ravet, Emmanuel, Zhong, Franklin, Cougoule, Céline, Planès, Rémi, Meunier, Etienne
Published 2023