Newer Approaches to Management of Retinal Degenerative Disorders: Gene Therapy and Cell Replacement Therapy

by LINGAM GOPAL, SU XINYI, BHARGAVA MAYURI, LIU ZENGPING, SWATHI LINGAM
Published 2021

A new highly transparent injectable PHA-based thermogelling vitreous substitute

by Xue, Kun, LIU ZENGPING, Jiang, Lu, Kai, Dan, Li, Zibiao, SU XINYI, XIAN JUN LOH
Published 2021

Dysfunctional autophagy, proteostasis, and mitochondria as a prelude to age-related macular degeneration

by Lenin, Raji Rajesh, Koh, Yi Hui, Zhang, Zheting, Yeo, Yan Zhuang, Parikh, Bhav Harshad, Seah, Ivan, Wong, Wendy, Su, Xinyi
Published 2023

PCL-Based Thermogelling Polymer: Molecular Weight Effects on Its Suitability as Vitreous Tamponade

by Xue, K, LIU ZENGPING, Lin, Q, Lim, JYC, Tang, KY, WONG SOO LIN, BHAV HARSHAD PARIKH, SU XINYI, Loh, XJ
Published 2021

Hints for Gentle Submacular Injection in Non-Human Primates Based on Intraoperative OCT Guidance

by Tan, Gavin SW, LIU ZENGPING, Ilmarinen, Tanja, VELUCHAMY AMUTHA BARATHI, Chee, Caroline K, LINGAM GOPAL, SU XINYI, Stanzel, Boris V
Published 2021

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

by Seah, Ivan, LIU ZENGPING, WONG SOO LIN, Wong, Wendy, Holder, Graham E, VELUCHAMY AMUTHA BARATHI, LINGAM GOPAL, SU XINYI, Stanzel, Boris
Published 2021

Use of biomaterials for sustained delivery for anti-VEGF to treat retinal diseases (Jan, 10.1038/s41433-020-0770-y, 2020)

by Seah, Ivan, Zhao, Xinxin, Lin, Qianyu, LIU ZENGPING, Su, Steven Zheng Zhe, YUEN YEW SEN, WALTER HUNZIKER, LINGAM GOPAL, XIAN JUN LOH, SU XINYI
Published 2021

Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases

by Seah, Ivan, Zhao, Xinxin, Lin, Qianyu, LIU ZENGPING, Su, Steven Zheng Zhe, YUEN YEW SEN, Hunziker, Walter, LINGAM GOPAL, XIAN JUN LOH, SU XINYI
Published 2021

Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources

by Regha, Kakkad, Bhargava, Mayuri, Al-Mubaarak, Abdurrahmaan, Chai, Chou, Parikh, Bhav Harshad, Liu, Zengping, Wong, Claudine See Wei, Hunziker, Walter, Lim, Kah Leong, Su, Xinyi
Published 2023

Injectable PTHF-based thermogelling polyurethane implants for long-term intraocular application

by Zhang, Kaiwen, Liu, Zengping, Lin, Qianyu, Boo, Yi Jian, Ow, Valerie, Zhao, Xinxin, Wong, Daniel Soo Lin, Lim, Jason YC, Xue, Kun, Su, Xinyi, Wu, Decheng, Loh, Xian Jun
Published 2023

Electrospun Pectin-Polyhydroxybutyrate Nanofibers for Retinal Tissue Engineering

by Chan, Siew Yin, Chan, Benjamin Qi Yu, LIU ZENGPING, Parikh, Bhav Harshad, Zhang, Kangyi, Lin, Qianyu, SU XINYI, Kai, Dan, Choo, Wee Sim, Young, David James, Loh X.J
Published 2021

Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model

by LIU ZENGPING, Ilmarinen, Tanja, Tan, Gavin SW, Hongisto, Heidi, Wong, Edmund YM, Tsai, Andrew SH, Al-Nawaiseh, Sami, Holder, Graham E, SU XINYI, VELUCHAMY AMUTHA BARATHI, Skottman, Heli, Stanzel, Boris
Published 2021

High molecular weight hyper-branched PCL-based thermogelling vitreous endotamponades

by Lin, Qianyu, LIU ZENGPING, Wong, Daniel SL, Lim, Chen Chuan, Liu, Connie K, Guo, Liangfeng, Zhao, Xinxin, Boo, Yi Jian, Wong, Joey HM, Tan, Rebekah PT, Xue, Kun, Lim, Jason YC, SU XINYI, XIAN JUN LOH
Published 2021

Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections

by Xue, Kun, Zhao, Xinxin, Zhang, Zhongxing, Qiu, Beiying, Tan, Queenie Shu Woon, Ong, Kok Haur, LIU ZENGPING, BHAV HARSHAD PARIKH, VELUCHAMY AMUTHA BARATHI, Yu, Weimiao, Wang, Xiaomeng, LINGAM GOPAL, Hunziker, Walter, SU XINYI, XIAN JUN LOH
Published 2021

Multi-species single-cell transcriptomic analysis of ocular compartment regulons

by Gautam, Pradeep, Hamashima, Kiyofumi, Chen, Ying, Zeng, Yingying, Makovoz, Bar, Parikh, Bhav Harshad, Lee, Hsin Yee, Lau, Katherine Anne, Su, Xinyi, Wong, Raymond C. B., Chan, Woon-Khiong, Li, Hu, Blenkinsop, Timothy A., Loh, Yuin-Han
Published 2022

Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

by Wu, Kan Xing, Yeo, Natalie Jia Ying, Ng, Chun Yi, Chioh, Florence Wen Jing, Fan, Qiao, Tian, Xianfeng, Yang, Binxia, Narayanan, Gunaseelan, Tay, Hui Min, Hou, Han Wei, Dunn, Norris Ray, Su, Xinyi, Cheung, Gemmy Chui Ming, Cheung, Christine
Published 2022

Gene-Based Therapeutics for Acquired Retinal Disease: Opportunities and Progress

by Tan, Tien-En, Fenner, Beau James, Barathi, Veluchamy Amutha, Tun, Sai Bo Bo, Wey, Yeo Sia, Tsai, Andrew Shih Hsiang, Su, Xinyi, Lee, Shu Yen, Cheung, Chui Ming Gemmy, Wong, Tien Yin, Mehta, Jodhbir Singh, Teo, Kelvin Yi Chong
Published 2022

A Pilot Study on MicroRNA Profile in Tear Fluid to Predict Response to Anti-VEGF Treatments for Diabetic Macular Edema

by Chan, Hwei Wuen, Yang, Binxia, Wong, Wendy, Blakeley, Paul, Seah, Ivan, Tan, Queenie Shu Woon, Wang, Haofei, Bhargava, Mayuri, Lin, Hazel Anne, Chai, Charmaine HC, Mangunkusumo, Erlangga Ariadarma, Thet, Naing, Yuen, Yew Sen, Sethi, Raman, Wang, Si, Hunziker, Walter, Lingam, Gopal, Su, Xinyi
Published 2021

cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates

by SWATHI LINGAM, LIU ZENGPING, Yang, Binxia, Wong, Wendy, BHAV HARSHAD PARIKH, Ong, Jun Yi, Goh, Debbie, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Tan, Gavin SW, Holder, Graham E, REGHA KAKKAD, VELUCHAMY AMUTHA BARATHI, Hunziker, Walter, LINGAM GOPAL, ZENG XIANMIN, SU XINYI
Published 2021

Impact of Microplastics on the Ocular Surface

by Wu, Duoduo, Lim, Blanche XH, Seah, Ivan, Xie, Shay, Jaeger, Julia E, Symons, Robert K, Heffernan, Amy L, Curren, Emily EM, Leong, Sandric CY, Riau, Andri K, Lim, Dawn KA, Stapleton, Fiona, Ali, Mohammad Javed, Singh, Swati, Tong, Louis, Mehta, Jodhbir S, Su, Xinyi, Lim, Chris HL
Published 2023