Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons

by Sharma, M, Dierkes, T, Sajikumar, S
Published 2020

Chelation of hippocampal zinc enhances long-term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memory

by Shetty, M.S, Sharma, M, Sajikumar, S
Published 2020

Epigenetics: the panacea for cognitive decline?

by Sharma, Mahima, Raghuraman, Radha, Sajikumar, Sreedharan
Published 2022

Alteration of hippocampal CA2 plasticity and social memory in adult rats impacted by juvenile stress

by Raghuraman, Radha, Navakkode, Sheeja, Sajikumar, Sreedharan
Published 2024

Dopamine induces LTP differentially in apical and basal dendrites through BDNF and voltage-dependent calcium channels

by Navakkode, S., Sajikumar, S., Korte, M., Soong, T.W.
Published 2014

Histone deacetylase 3 inhibition re-establishes synaptic tagging and capture in aging through the activation of nuclear factor kappa B

by Sharma, M, Shetty, M.S, Arumugam, T.V, Sajikumar, S
Published 2020

Role of microglia in long-term potentiation and synaptic tagging/capture

by Raghuraman, Radha, Rangarajan, Parakalan, Dheen, Shaikali Thameem, Sreedharan, Sajikumar
Published 2020

Activation of microglia in acute hippocampal slices affects activity-dependent long-term potentiation and synaptic tagging and capture in area CA1

by Raghuraman, Radha, Karthikeyan, Aparna, Wei, Wong Lik, Dheen, S Thameem, Sajikumar, Sreedharan
Published 2020

Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in rats

by Saw, Genevieve, Krishna, Kumar, Gupta, Neelima, Soong, Tuck Wah, Mallilankaraman, Karthik, Sajikumar, Sreedharan, Dheen, S Thameem
Published 2020

ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing A beta impairment of insulin signaling in an Alzheimer's disease mouse model

by Chan, Elizabeth S, Shetty, Mahesh Shivarama, Sajikumar, Sreedharan, Chen, Christopher, Soong, Tuck Wah, Wong, Boon-Seng
Published 2022

Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area o...

by Han, Javan Lee Tze, Pang, Karen Ka Lam, Ang, Sheila Rui Xia, Sharma, Mahima, Sajikumar, Sreedharan
Published 2022

Group III metabotropic glutamate receptors gate long-term potentiation and synaptic tagging/capture in rat hippocampal area CA2

by Dasgupta, A., Lim, Y.J., Kumar, K., Baby, N., Pang, K.L.K., Benoy, A., Behnisch, T., Sajikumar, S.
Published 2021

Inactive variants of death receptor p75(NTR) reduce Alzheimer's neuropathology by interfering with APP internalization (vol 40, e104450, 2021)

by Yi, Chenju, Goh, Ket Yin, Wong, Lik-Wei, Ramanujan, Ajeena, Tanaka, Kazuhiro, Sajikumar, Sreedharan, Ibanez, Carlos F
Published 2022

Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes

by Garcia-Alvarez, G, Shetty, M.S, Lu, B, Yap, K.A.F, Oh-Hora, M, Sajikumar, S, Bichler, Z, Fivaz, M
Published 2020

Loss of CaV1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory

by Zhai, J, Navakkode, S, Yeow, SQZ, Krishna-K, K, Liang, MC, Koh, JH, Wong, RX, Yu, WP, Sajikumar, S, Huang, H, Soong, TW
Published 2023

Deletion of CD137 ligand exacerbates renal and cutaneous but alleviates cerebral manifestations in Lupus

by Mak, A., Dharmadhikari, B., Kow, N.Y., Thamboo, T.P., Tang, Q., Wong, L.W., Sajikumar, S., Wong, H.Y., Schwarz, H.
Published 2021

Sex-specific accelerated decay in time/activity-dependent plasticity and associative memory in an animal model of Alzheimer's disease

by Navakkode, Sheeja, Gaunt, Jessica Ruth, Pavon, Maria Vazquez, Bansal, Vibhavari Aysha, Abraham, Riya Prasad, Chong, Yee Song, Ch'ng, Toh Hean, Sajikumar, Sreedharan
Published 2022

Sex-specific accelerated decay in time/activity-dependent plasticity and associative memory in an animal model of Alzheimer's disease

by Navakkode, Sheeja, Gaunt, Jessica Ruth, Pavon, Maria Vazquez, Bansal, Vibhavari Aysha, Abraham, Riya Prasad, Chong, Yee Song, Ch'ng, Toh Hean, Sajikumar, Sreedharan
Published 2022

Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity

by Chong, Yee Song, Wong, Lik-Wei, Gaunt, Jessica, Lee, Yan Jun, Goh, Cai Shan, Morris, Richard GM, Ch'ng, Toh Hean, Sajikumar, Sreedharan
Published 2023

Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity

by Chew B., Ryu J.R., Ng T., Ma D., Dasgupta A., NEO SIN HUI, Zhao J., Zhong Z., Bichler Z., Sajikumar S., Goh E.L.K.
Published 2020