Sphingolipids and insulin resistance: The five Ws

by Summers, S.A.
Published 2016

50th international conference on the bioscience of lipids

by Summers, S.A.
Published 2016

Ceramides as modulators of cellular and whole-body metabolism

by Bikman, B.T., Summers, S.A.
Published 2016

Lipids in Human Diseases

by Siddique, M.M., Summers, S.A.
Published 2014

Lipid oversupply, selective insulin resistance, and lipotoxicity: Molecular mechanisms

by Chavez, J.A., Summers, S.A.
Published 2016

A ceramide-centric view of insulin resistance

by Chavez, J.A., Summers, S.A.
Published 2016

Ceramides and glucosylceramides are independent antagonists of insulin signaling

by Chavez, J.A., Siddique, M.M., Wang, S.T., Ching, J., Shayman, J.A., Summers, S.A.
Published 2014

Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro

by Siddique, M.M., Bikman, B.T., Wang, L., Ying, L., Reinhardt, E., Shui, G., Wenk, M.R., Summers, S.A.
Published 2014

Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling

by Siddique M.M., Li Y., Wang L., Ching J., Mal M., Ilkayeva O., Wu, Y.J., Bay B.-H., Summers S.A.
Published 2020

Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis

by Bikman, B.T., Guan, Y., Shui, G., Siddique, M.M., Holland, W.L., Kim, J.Y., Fabriàs, G., Wenk, M.R., Summers, S.A.
Published 2014

Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue

by Kolak, M., Gertow, J., Westerbacka, J., Summers, S.A., Liska, J., Franco-Cereceda, A., Orei, M., Yki-Järvinen, H., Eriksson, P., Fisher, R.M.
Published 2016

ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs

by Lee, M.H, Goralczyk, A.G, Kriszt, R, Ang, X.M, Badowski, C, Li, Y, Summers, S.A, Toh, S.-A, Yassin, M.S, Shabbir, A, Sheppard, A, Raghunath, M
Published 2020

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

by Holland, W.L., Bikman, B.T., Wang, L.-P., Yuguang, G., Sargent, K.M., Bulchand, S., Knotts, T.A., Shui, G., Clegg, D.J., Wenk, M.R., Pagliassotti, M.J., Scherer, P.E., Summers, S.A.
Published 2014

Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans

by Chua, E.C.-P., Shui, G., Lee, I.T.G., Lau, P., Tan, L.-C., Yeo, S.-C., Lam, B.D., Bulchand, S., Summers, S.A., Puvanendran, K., Rozen, S.G., Wenk, M.R., Gooley, J.J.
Published 2014

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

by Sinha, R.A., You, S.-H., Zhou, J., Siddique, M.M., Bay, B.-H., Zhu, X., Privalsky, M.L., Cheng, S.-Y., Stevens, R.D., Summers, S.A., Newgard, C.B., Lazar, M.A., Yen, P.M.
Published 2014

Molecular pathways reflecting poor intrauterine growth are found in Wharton's jelly-derived mesenchymal stem cells

by Sukarieh R., Joseph R., Leow S.C., Li Y., Löffler M., Aris I.M., Tan J.H., Teh A.L., Chen L., Holbrook J.D., Ng K., Lee Y.S., Chong Y.S., Summers S.A., Gluckman P.D., Stünkel W.
Published 2021

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

by Sinha R.A., Farah B.L., Singh B.K., Siddique M.M., Li Y., Wu Y., Ilkayeva O.R., Gooding J., Ching J., Zhou J., Martinez L., Xie S., Bay B.-H., Summers S.A., Newgard C.B., Yen P.M.
Published 2020

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

by Holland, W.L., Miller, R.A., Wang, Z.V., Sun, K., Barth, B.M., Bui, H.H., Davis, K.E., Bikman, B.T., Halberg, N., Rutkowski, J.M., Wade, M.R., Tenorio, V.M., Kuo, M.-S., Brozinick, J.T., Zhang, B.B., Birnbaum, M.J., Summers, S.A., Scherer, P.E.
Published 2016

Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

by de Carvalho, Leonardo P, Tan, Sock Hwee, Ow, Ghim-Siong, Tang, Zhiqun, Ching, Jianhong, Kovalik, Jean-Paul, Poh, Sock Cheng, Chin, Chee-Tang, Richards, A Mark, Martinez, Eliana C, Troughton, Richard W, Fong, Alan Yean-Yip, Yan, Bryan P, Seneviratna, Aruni, Sorokin, Vitaly, Summers, Scott A, Kuznetsov, Vladimir A, Chan, Mark Y
Published 2021

Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex

by Zhang, Q.-J., Holland, W.L., Wilson, L., Tanner, J.M., Kearns, D., Cahoon, J.M., Pettey, D., Losee, J., Duncan, B., Gale, D., Kowalski, C.A., Deeter, N., Nichols, A., Deesing, M., Arrant, C., Ruan, T., Boehme, C., McCamey, D.R., Rou, J., Ambal, K., Narra, K.K., Summers, S.A., Abel, E.D., Symons, J.D.
Published 2016