Unliganded TRs regulate growth and developmental timing during early embryogenesis: Evidence for a dual function mechanism of TR action

by Yen, P.M
Published 2020

Thyroid hormone-mediated autophagy and mitochondrial turnover in NAFLD

by Sinha, R.A, Yen, P.M
Published 2020

Novel transcriptional mechanisms for regulating metabolism by thyroid hormone

by Singh, B.K, Sinha, R.A, Yen, P.M
Published 2020

Hyperthyroidism in the personalized medicine era: The rise of mathematical optimization

by Meng F., Li E., Yen P.M., Leow M.K.S.
Published 2020

Profiling retrospective thyroid function data in complete thyroidectomy patients to investigate the HPT axis set point (PREDICT-IT)

by Li E., Yen P.M., Dietrich J.W., Leow M.K.-S.
Published 2020

Distinct and Histone-Specific Modifications Mediate Positive versus Negative Transcriptional Regulation of TSHα Promoter

by Wang D., Xia X., Weiss R.E., Refetoff S., Yen P.M.
Published 2018

Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors

by Culhane, J.C., Wang, D., Yen, P.M., Cole, P.A.
Published 2016

Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells

by Yap, C.S., Sinha, R.A., Ota, S., Katsuki, M., Yen, P.M.
Published 2016

Resveratrol induces insulin gene expression in mouse pancreatic ?-cells

by Xie, S, Sinha, R.A, Singh, B.K, Li, G.D, Han, W, Yen, P.M
Published 2020

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N6-methyladenosine demethylase activity in cells

by Cheong, A., Low, J.J.A., Lim, A., Yen, P.M., Woon, E.C.Y.
Published 2022

Metabolomic analysis shows differential hepatic effects of T 2 and T 3 in rats after short-term feeding with high fat diet

by Iannucci, L.F, Cioffi, F, Senese, R, Goglia, F, Lanni, A, Yen, P.M, Sinha, R.A
Published 2020

FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes

by Singh, B.K., Sinha, R.A., Zhou, J., Xie, S.Y., You, S.-H., Gauthier, K., Yen, P.M.
Published 2014

PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA

by Wang, G., Cao, X., Lai, S., Luo, X., Feng, Y., Xia, X., Yen, P.M., Gong, J., Hu, J.
Published 2016

Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by vitamin B supplementation

by Tripathi, M, Zhang, C.W, Singh, B.K, Sinha, R.A, Moe, K.T, Desilva, D.A, Yen, P.M
Published 2020

Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease

by Farah, B.L., Madden, L., Li, S., Nance, S., Bird, A., Bursac, N., Yen, P.M., Young, S.P., Koeberl, D.D.
Published 2016

Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

by Wang, M.-E, Singh, B.K, Hsu, M.-C, Huang, C, Yen, P.M, Wu, L.-S, Jong, D.-S, Chiu, C.-H
Published 2020

Renal endoplasmic reticulum stress is coupled to impaired autophagy in a mouse model of GSD Ia

by Farah B.L., Landau D.J., Wu Y., Sinha R.A., Loh A., Bay B.-H., Koeberl D.D., Yen P.M.
Published 2020

Thyroid hormone stimulation of autophagy is essential for mitochondrial biogenesis and activity in skeletal muscle

by Lesmana R., Sinha R.A., Singh B.K., Zhou J., Ohba K., Wu Y., Yau W.W., Bay B.-H., Yen P.M.
Published 2020

Desensitization and incomplete recovery of hepatic target genes after chronic thyroid hormone treatment and withdrawal in male adult mice

by Ohba K., Leow M.K.-S., Singh B.K., Sinha R.A., Lesmana R., Liao X.-H., Ghosh S., Refetoff S., Sng J.C.G., Yen P.M.
Published 2020

Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa)

by Farah B.L., Sinha R.A., Wu Y., Singh B.K., Lim A., Hirayama M., Landau D.J., Bay B.H., Koeberl D.D., Yen P.M.
Published 2020