In vitro and in vivo study of ABT-869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors: insight into molecular mechanism and b...

by ZHOU JIANBIAO
Published 2010

ONCOGENES IN CHILDHOOD ACUTE LEUKEMIA

by ZHOU JIANBIAO
Published 2019

ONCOGENES IN CHILDHOOD ACUTE LEUKEMIA

by ZHOU JIANBIAO
Published 2019

Biological Hallmarks and Emerging Strategies to Target STAT3 Signaling in Multiple Myeloma

by Zhou, Jianbiao, Chng, Wee-Joo
Published 2022

Novel mechanism of drug resistance to proteasome inhibitors in multiple myeloma.

by Zhou, Jianbiao, Chng, Wee-Joo
Published 2022

Crosstalk between endoplasmic reticulum stress and oxidative stress: a dynamic duo in multiple myeloma

by Xiong, Sinan, Chng, Wee-Joo, Zhou, Jianbiao
Published 2021

Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

by Ang, Daniel Aron, Carter, Jean-Michel, Deka, Kamalakshi, Tan, Joel H. L., Zhou, Jianbiao, Chen, Qingfeng, Chng, Wee Joo, Harmston, Nathan, Li, Yinghui
Published 2024

NF-kappa B promotes the stem-like properties of leukemia cells by activation of LIN28B

by Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo
Published 2022

Non-canonical activation of beta-catenin by PRL-3 phosphatase in acute myeloid leukemia

by Chong, Phyllis SY, Zhou, Jianbiao, Chooi, Jing-Yuan, Chan, Zit-Liang, Toh, Sabrina Hui Min, Tan, Tuan Zea, Wee, Sheena, Gunaratne, Jayantha, Zeng, Qi, Chng, Wee-Joo
Published 2020

Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling

by Ng, Siok-Bian, Selvarajan, Viknesvaran, Huang, Gaofeng, Zhou, Jianbiao, Feldman, Andrew L, Law, Mark, Kwong, Yok-Lam, Shimizu, Norio, Kagami, Yoshitoyo, Aozasa, Katsuyuki, Salto-Tellez, Manuel, Chng, Wee-Joo
Published 2021

IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple Myeloma

by Chong, Phyllis SY, Zhou, Jianbiao, Lim, Julia SL, Hee, Yan Ting, Chooi, Jing-Yuan, Chung, Tae-Hoon, Tan, Zea Tuan, Zeng, Qi, Waller, Daniel D, Sebag, Michael, Chng, Wee-Joo
Published 2020

PCBP1 Suppresses the Translation of Metastasis-Associated PRL-3 Phosphatase

by Wang, Haihe, Vardy, Leah A, Tan, Cheng Peow, Loo, Jia Min, Guo, Ke, Li, Jie, Lim, Seng Gee, Zhou, Jianbiao, Chng, Wee Joo, Ng, Siok Bian, Li, Hui Xiang, Zeng, Qi
Published 2021

Functional characterization of D9, a novel deazaneplanocin a (DZNep) analog, in targeting acute myeloid leukemia (AML)

by Jiang, Xia, Lim, Cheryl Zi Hui, Li, Zhimei, Lee, Puayleng, Yatim, Siti Maryam J. M., Guan, Peiyong, Li, Juntao, Zhou, Jianbiao, Pan, Jingxuan, Chng, Wee Joo, Chai, Li Lin Christina, Yu, Qiang
Published 2015

Engineering the First Chimeric Antibody in Targeting Intracellular PRL-3 Oncoprotein for Cancer Therapy in Mice

by Guo, Ke, Tang, Jing Ping, Jie, Li, Al-Aidaroos, Abdul Qader O, Hong, Cheng William, Tan, Cheng Peow Bobby, Park, Jung Eun, Varghese, Leyon, Feng, Zhiwei, Zhou, Jianbiao, Chng, Wee Joo, Zeng, Qi
Published 2021

Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice

by Guo, Ke, Tang, Jing Ping, Jie, Li, Hong, Cheng William, Tan, Cheng Peow Bobby, Park, Jung Eun, Varghese, Leyon, Feng, Zhiwei, Zhou, Jianbiao, Chng, Wee Joo, Zeng, Qi, Al-Aidaroos, Abdul Qader O.
Published 2013

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.

by Zhou, Jianbiao, Yiying Quah, Jessie, Ng, Yvonne, Chooi, Jing-Yuan, Hui-Min Toh, Sabrina, Lin, Baohong, Zea Tan, Tuan, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, Lisa AG, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo
Published 2022

Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa J, Xiong, Sinan, Toh, Sabrina HM, Balan, Kalpnaa, Wong, Regina WJ, Lim, Julia SL, Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Published 2023

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Wong, Regina Wan Ju, Chooi, Jing-Yuan, Lim, Julia Sze Lynn, Sanda, Takaomi, Ooi, Melissa, De Mel, Sanjay, Soekojo, Cinnie, Chen, Yongxia, Zhang, Enfan, Cai, Zhen, Shen, Peng, Ruan, Jian, Chng, Wee-Joo
Published 2021

Super enhancer-mediated upregulation of HJURP promotes growth and survival of t(4;14)-positive multiple myeloma

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa Jane, Xiong, Sinan, Toh, Sabrina H. M., Balan, Kalpnaa, Wong, Regina W. J., Lim, Julia S. L., Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Published 2022

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML

by Zhou, Jianbiao, Chan, Zit-Liang, Bi, Chonglei, Lu, Xiao, Chong, Phyllis SY, Chooi, Jing-Yuan, Cheong, Lip-Lee, Liu, Shaw-Cheng, Ching, Ying Qing, Zhou, Yafeng, Osato, Motomi, Tan, Tuan Zea, Ng, Chin Hin, Ng, Siok-Bian, Wang, Shi, Zeng, Qi, Chng, Wee-Joo
Published 2021