PHARMACOKINETICS AND PHARMACODYNAMICS EVALUATION OF MATRIX-TYPE PATCHES CONTAINING QUININE IN MALE WISTAR RATS
Nocturnal leg cramps are painful muscle contractions occured in the leg in the night, that may cause sleep deprivation. Quinine administered orally is an effective pharmacological therapy for the treatment of nocturnal leg cramps, however it has significant side effects. Transdermal matrix patch...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/45228 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |