PHARMACOKINETIC AND PHARMACODYNAMIC OF MATRIX-TYPE QUININE PATCH USING COSOLVENT TO ENCHANCE WATER SOLUBILITY
Leg cramp is defined as spasticity, shortening, feeling stuck, or the tension on the leg muscles. Leg cramp that occur when sleeping at night called as nocturnal leg cramps. Matrix-type transdermal quinine patch has been developed in previous studies with increasing the solubility of quinine in wate...
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Format: | Theses |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/78771 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |