CHARACTERIZATION OF NUDT15 GENETIC VARIATIONS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
6-Mercaptopurine (6-MP) is one of the main chemotherapy agents in the maintenance phase of therapy for acute lymphoblastic leukemia (LLA). Genetic variations in the nudix hydrolase 15 (NUDT15) gene have been studied as important determinants of 6-MP intolerance and hematopoietic toxicity in pediat...
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| Format: | Final Project |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/82623 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |