VALIDITAS DIAGNOSTIK METODE CEPAT IgM JE (JAPANESE ENCHEPALITIS) PADA PASIEN SUSPEK JE DI BALI

• Main Authors: , IRIANI SAMAD, , dr. Andaru Dahesihdewi, M.Kes, Sp.PK(K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/119561/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59564
• Institution: Universitas Gadjah Mada

Background: Clinical symptoms of the Japanese encephalitis disease are difficult to distinguish from other encephalitis diseases, clinical diagnosis to be supported by the examination of isolation or serology. There are several technique to support the diagnosis of JE examination but still have limited. Based on this reasoning need for a rapid test with good accuracy that can be used in primary care health centers, especially in highly endemic areas. Objective: This study aimed to evaluate diagnostic validity of JE IgM rapid methods in serum of patients with encephalitis. Method: This study use cross-sectional design, for diagnose test with 176 serum samples, independen and blind, JE IgM rapid method compared to methods (ELISA IgM). Serum samples are stored in the BLK of Bali 2002-2007. Results: The results of the diagnostic test using a 2x2 table, the results is sensitivity of 23% (CI :12-35%), specificity 99% (CI: 98-100%), Positive Predictive Value 92% (CI: 78-100% ), Accuracy 76.7%, Negative Predictive Value of 75% (CI :69-82%), Positive Likelihood Ratio 28.62 (:3,82 CI-214, 46), Negative Likelihood Ratio 0.78 (CI: 0 0.67-0, 90 Conclusion: These result show that JE IgM rapid method for patients with encephalitis were compared to the ELISA IgM method have gives results specificity value of 99% (CI: 98-100%)