PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS
Background: Diabetes mellitus (DM), a degenerative disease, is a metabolic disorder characterized by high levels of glucose in the blood. The prevalence of diabetes continues to rise and will be a serious health problem. Noni is an alternative functional foods that have hypoglycemic effects. Noni ha...
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[Yogyakarta] : Universitas Gadjah Mada
2013
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id-ugm-repo.1219682016-03-04T08:40:16Z https://repository.ugm.ac.id/121968/ PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS , MEITA ROCHMAWANGI , Prof. Dr. Ir. Y. Marsono, MS ETD Background: Diabetes mellitus (DM), a degenerative disease, is a metabolic disorder characterized by high levels of glucose in the blood. The prevalence of diabetes continues to rise and will be a serious health problem. Noni is an alternative functional foods that have hypoglycemic effects. Noni has a pungent odor and unpleasant. Freeze juicing extraction method is an alternative to the simple extraction to minimize the lack of it. Objective: This study aimed to determine the effect of noni extract \"freeze juicing\" on blood glucose levels wistar rats with diabetes mellitus. Method: The type of this research was a quasi experimental study with a type of design form, pre and post test control group design. Subject of this study is thirty Wistar rats aged 2 months and weighs about 160-180 grams. Rats were divided into 5 groups: negative control, positive control, freeze juicing noni doses of 0.25, 0.50 doses, and 1 dose during 28 days of treatment. Rats were adapted for 3 days, then fasted rats before induction of nicotinamide 110 mg and 45 mg streptozotocin. Analysis of blood glucose level was as much as 2 times (pre and post test). Data were analyzed using ANOVA. The results: Wistar rats was induced by streptozotocin and nicotinamide had increase blood glucose levels by an average blood glucose> 200 mg / dl. Statistical tests were conducted to determine the changes in blood glucose levels from pre-test to post test showed no significant difference between groups with p> 0.05. Juicing freeze noni extract had no effect on blood glucose levels decrease DM Wistar rats. Although the 0.5 dose group but decreased in the positive control group also decreased. Conclusions: Freeze juicing noni extract had no effect on blood glucose levels in Wistar rats with diabetes mellitus. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , MEITA ROCHMAWANGI and , Prof. Dr. Ir. Y. Marsono, MS (2013) PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=62067 |
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ETD , MEITA ROCHMAWANGI , Prof. Dr. Ir. Y. Marsono, MS PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
description |
Background: Diabetes mellitus (DM), a degenerative disease, is a metabolic
disorder characterized by high levels of glucose in the blood. The prevalence of
diabetes continues to rise and will be a serious health problem. Noni is an
alternative functional foods that have hypoglycemic effects. Noni has a pungent
odor and unpleasant. Freeze juicing extraction method is an alternative to the
simple extraction to minimize the lack of it.
Objective: This study aimed to determine the effect of noni extract \"freeze
juicing\" on blood glucose levels wistar rats with diabetes mellitus.
Method: The type of this research was a quasi experimental study with a type of
design form, pre and post test control group design. Subject of this study is thirty
Wistar rats aged 2 months and weighs about 160-180 grams. Rats were divided
into 5 groups: negative control, positive control, freeze juicing noni doses of 0.25,
0.50 doses, and 1 dose during 28 days of treatment. Rats were adapted for 3
days, then fasted rats before induction of nicotinamide 110 mg and 45 mg
streptozotocin. Analysis of blood glucose level was as much as 2 times (pre and
post test). Data were analyzed using ANOVA.
The results: Wistar rats was induced by streptozotocin and nicotinamide had
increase blood glucose levels by an average blood glucose> 200 mg / dl.
Statistical tests were conducted to determine the changes in blood glucose levels
from pre-test to post test showed no significant difference between groups with
p> 0.05. Juicing freeze noni extract had no effect on blood glucose levels
decrease DM Wistar rats. Although the 0.5 dose group but decreased in the
positive control group also decreased.
Conclusions: Freeze juicing noni extract had no effect on blood glucose levels in
Wistar rats with diabetes mellitus. |
format |
Theses and Dissertations NonPeerReviewed |
author |
, MEITA ROCHMAWANGI , Prof. Dr. Ir. Y. Marsono, MS |
author_facet |
, MEITA ROCHMAWANGI , Prof. Dr. Ir. Y. Marsono, MS |
author_sort |
, MEITA ROCHMAWANGI |
title |
PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
title_short |
PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
title_full |
PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
title_fullStr |
PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
title_full_unstemmed |
PENGARUH PEMBERIAN EKSTRAK MENGKUDU (Morinda citrifolia L.) �FREEZE JUICING� TERHADAP KADAR GLUKOSA DARAH TIKUS WISTAR DIABETES MELLITUS |
title_sort |
pengaruh pemberian ekstrak mengkudu (morinda citrifolia l.) �freeze juicing� terhadap kadar glukosa darah tikus wistar diabetes mellitus |
publisher |
[Yogyakarta] : Universitas Gadjah Mada |
publishDate |
2013 |
url |
https://repository.ugm.ac.id/121968/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=62067 |
_version_ |
1681231614234853376 |