A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model

A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model

Background: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic mortality. The objective of this study was to investigate the therapeutic potential of a novel potent histone deacetylase (HDAC) inhibitor MPT0E028 on emphysema. Materials and Methods: A mouse model of porcine pa...

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Main Authors: Yeh, Lu-Yang, Fang, Yu-Ting, Lee, Hong-Sheng, Liu, Chia-Hao, Chen, You-Yin, Lo, Yu-Chun, Laiman, Vincent, Liou, Jing-Ping, Chung, Kian Fan, Chuang, Hsiao-Chi, Lin, Chien-Huang
Format: Article PeerReviewed
Language:English
Published: Frontier 2022
Subjects:
Clinical Sciences
Online Access:https://repository.ugm.ac.id/278934/1/Laiman_KKMK.pdf
https://repository.ugm.ac.id/278934/
https://www.frontiersin.org/articles/10.3389/fmed.2022.794025/full
https://doi.org/10.3389/fmed.2022.794025
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Institution: Universitas Gadjah Mada
Language: English

Internet

https://repository.ugm.ac.id/278934/1/Laiman_KKMK.pdf
https://repository.ugm.ac.id/278934/
https://www.frontiersin.org/articles/10.3389/fmed.2022.794025/full
https://doi.org/10.3389/fmed.2022.794025

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