A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model
Background: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic mortality. The objective of this study was to investigate the therapeutic potential of a novel potent histone deacetylase (HDAC) inhibitor MPT0E028 on emphysema. Materials and Methods: A mouse model of porcine pa...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English |
| Published: |
Frontier
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/278934/1/Laiman_KKMK.pdf https://repository.ugm.ac.id/278934/ https://www.frontiersin.org/articles/10.3389/fmed.2022.794025/full https://doi.org/10.3389/fmed.2022.794025 |
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| Institution: | Universitas Gadjah Mada |
| Language: | English |