A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model

A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model

Background: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic mortality. The objective of this study was to investigate the therapeutic potential of a novel potent histone deacetylase (HDAC) inhibitor MPT0E028 on emphysema. Materials and Methods: A mouse model of porcine pa...

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Main Authors:	Yeh, Lu-Yang, Fang, Yu-Ting, Lee, Hong-Sheng, Liu, Chia-Hao, Chen, You-Yin, Lo, Yu-Chun, Laiman, Vincent, Liou, Jing-Ping, Chung, Kian Fan, Chuang, Hsiao-Chi, Lin, Chien-Huang
格式:	Article PeerReviewed
語言:	English
出版:	Frontier 2022
主題:	Clinical Sciences
在線閱讀:	https://repository.ugm.ac.id/278934/1/Laiman_KKMK.pdf https://repository.ugm.ac.id/278934/ https://www.frontiersin.org/articles/10.3389/fmed.2022.794025/full https://doi.org/10.3389/fmed.2022.794025
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