Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells

Background Airway fibrosis is one of the pathological characteristics of severe asthma. Transforming growth factor (TGF)-β has been known to promote epithelial-mesenchymal transition formation and to play a role in the progression of tissue fibrosis. Cellular communication network factor 2 (CCN2)...

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Bibliographic Details
Main Authors: Cheng, Wun-Hao, Kao, Shih-Ya, Chen, Chia-Ling, Yuliani, Fara Silvia, Lin, Lee-Yuan, Lin, Chien-Huang, Chen, Bing-Chang
Format: Article PeerReviewed
Language:English
Published: Springer Nature 2022
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Online Access:https://repository.ugm.ac.id/283164/1/s12931-022-02285-2.pdf
https://repository.ugm.ac.id/283164/
https://respiratory-research.biomedcentral.com/
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Institution: Universitas Gadjah Mada
Language: English