Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells
Background: Airway fibrosis is one of the pathological characteristics of severe asthma. Transforming growth factor (TGF)‑β has been known to promote epithelial‑mesenchymal transition formation and to play a role in the progres‑ sion of tissue fibrosis. Cellular communication network factor 2 (CCN...
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Main Authors: | , , , , , , |
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Format: | Article PeerReviewed |
Language: | English |
Published: |
Springer
2022
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Subjects: | |
Online Access: | https://repository.ugm.ac.id/278652/1/Yuliani_KKMK.pdf https://repository.ugm.ac.id/278652/ https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-022-02285-2 https://doi.org/10.1186/s12931-022-02285-2 |
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Institution: | Universitas Gadjah Mada |
Language: | English |