A revisit into the Den2 NS2B/NS3 virus protease homology model: Structural verification and comparison with crystal structure of HCV NS3/4A and Den2 NS3

A revisit into the Den2 NS2B/NS3 virus protease homology model: Structural verification and comparison with crystal structure of HCV NS3/4A and Den2 NS3

Although the crystal structure of DEN2 NS3 serine protease has been reported, the proteolytic mechanism of this enzyme in the presence of NS2B as co-factor which greatly enhances its activity is not well-understood. Using the homology model of DEN2 NS3 co-complexed with NS2B co-factor based on HCV N...

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Bibliographic Details
Main Authors: Lee, Y.K., Othman, R., Abdul Wahab, H., Yusof, Rohana, Rahman, N.A.
Format: Article
Published: Faculty of Science, University of Malaya 2006
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/7139/
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Institution: Universiti Malaya

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http://eprints.um.edu.my/7139/

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