Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread

Hypertension is a major risk factor of cardiovascular diseases globally. Studies have shown that there is a positive association between seaweed intake and lower blood pressure as indicated in animal studies as well as limited human trials. Hence, this study was designed to investigate the hypotensi...

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Main Author: Noraidah Haini
Format: Thesis
Language:English
English
Published: 2017
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spelling my.ums.eprints.377102023-11-29T02:22:05Z https://eprints.ums.edu.my/id/eprint/37710/ Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread Noraidah Haini TP1-1185 Chemical technology Hypertension is a major risk factor of cardiovascular diseases globally. Studies have shown that there is a positive association between seaweed intake and lower blood pressure as indicated in animal studies as well as limited human trials. Hence, this study was designed to investigate the hypotensive effect of Sargassum polycystum (SP) enriched bread on blood pressure among pre-hypertensive subjects. In this open label crossover trial, 12 subjects were randomly divided into two groups, who later received seaweed bread and control bread for 8 weeks with two months washout period. 5. po/ycystum powder (5 - 25%) was incorporated with wheat flour in producing yeast breads. These formulated breads were examined for their nutritional composition, antioxidant activities and sensory acceptance. The study showed that nutritional values of seaweed breads were significantly different from the control bread (p<0.05); wherein SP enriched breads contained ash ( 1.16 - 4.74%), moisture (34.65 - 37.57%), crude fat (6.45 - 6.98%), crude protein (8.74 - 8.92%), dietary fibre (2.26 - 9.71 %) on dry weight basis, besides having significant composition of macro minerals (Na, K, Ca and Mg) content. Ethanolic extracts of S. polycystum enriched breads possessed significantly higher total phenolic content (5.34 - 13.85 mg PGE/g dry extract), ferric reducing antioxidant power (FRAP) (122.89 - 162.06 μM FE/g dry extract) and DPPH radical scavenging activity (2.09 - 9.07 mg/ml) than water extracts (p<0.05). Sensory evaluation of breads using hedonic test has shown that bread enriched with 10% SP powder was selected as the best formulation among all seaweed breads (p<0.05), whereby its shelf life test showed that it is safe for 7-day consumption. In vitro test of antihypertensive assay showed that SP powder (0.41 mg/ml) and 10% seaweed bread (3.13 mg/ml) possessed higher ACE-inhibitor capacities than the control bread (25.01 mg/ml) (p<0.05). Intervention trial showed that subjects consuming seaweed bread resulted in significantly lower systolic blood pressure, diastolic blood pressure, pulse and total cholesterol (p<0.05). On contrary, subjects consuming control bread showed that there was no significant change in diastolic blood pressure but their systolic blood pressure, pulse and total cholesterol were significantly higher than the baseline (p<0.05). On the whole, the new therapeutic discovery of hypotensive effect in SP powder would contribute to health-promoting properties of seaweed as well as providing useful information to local industries for potential development of food and health products. 2017 Thesis NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/37710/1/24%20PAGES.pdf text en https://eprints.ums.edu.my/id/eprint/37710/2/FULLTEXT.pdf Noraidah Haini (2017) Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread. Masters thesis, Universiti Malaysia Sabah.
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic TP1-1185 Chemical technology
spellingShingle TP1-1185 Chemical technology
Noraidah Haini
Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
description Hypertension is a major risk factor of cardiovascular diseases globally. Studies have shown that there is a positive association between seaweed intake and lower blood pressure as indicated in animal studies as well as limited human trials. Hence, this study was designed to investigate the hypotensive effect of Sargassum polycystum (SP) enriched bread on blood pressure among pre-hypertensive subjects. In this open label crossover trial, 12 subjects were randomly divided into two groups, who later received seaweed bread and control bread for 8 weeks with two months washout period. 5. po/ycystum powder (5 - 25%) was incorporated with wheat flour in producing yeast breads. These formulated breads were examined for their nutritional composition, antioxidant activities and sensory acceptance. The study showed that nutritional values of seaweed breads were significantly different from the control bread (p<0.05); wherein SP enriched breads contained ash ( 1.16 - 4.74%), moisture (34.65 - 37.57%), crude fat (6.45 - 6.98%), crude protein (8.74 - 8.92%), dietary fibre (2.26 - 9.71 %) on dry weight basis, besides having significant composition of macro minerals (Na, K, Ca and Mg) content. Ethanolic extracts of S. polycystum enriched breads possessed significantly higher total phenolic content (5.34 - 13.85 mg PGE/g dry extract), ferric reducing antioxidant power (FRAP) (122.89 - 162.06 μM FE/g dry extract) and DPPH radical scavenging activity (2.09 - 9.07 mg/ml) than water extracts (p<0.05). Sensory evaluation of breads using hedonic test has shown that bread enriched with 10% SP powder was selected as the best formulation among all seaweed breads (p<0.05), whereby its shelf life test showed that it is safe for 7-day consumption. In vitro test of antihypertensive assay showed that SP powder (0.41 mg/ml) and 10% seaweed bread (3.13 mg/ml) possessed higher ACE-inhibitor capacities than the control bread (25.01 mg/ml) (p<0.05). Intervention trial showed that subjects consuming seaweed bread resulted in significantly lower systolic blood pressure, diastolic blood pressure, pulse and total cholesterol (p<0.05). On contrary, subjects consuming control bread showed that there was no significant change in diastolic blood pressure but their systolic blood pressure, pulse and total cholesterol were significantly higher than the baseline (p<0.05). On the whole, the new therapeutic discovery of hypotensive effect in SP powder would contribute to health-promoting properties of seaweed as well as providing useful information to local industries for potential development of food and health products.
format Thesis
author Noraidah Haini
author_facet Noraidah Haini
author_sort Noraidah Haini
title Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
title_short Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
title_full Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
title_fullStr Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
title_full_unstemmed Nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (Sargassum polycystum) enriched bread
title_sort nutritional composition, antioxidant activity and hypotensive effect of brown seaweed (sargassum polycystum) enriched bread
publishDate 2017
url https://eprints.ums.edu.my/id/eprint/37710/1/24%20PAGES.pdf
https://eprints.ums.edu.my/id/eprint/37710/2/FULLTEXT.pdf
https://eprints.ums.edu.my/id/eprint/37710/
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