Stochastic process algebra model of amyloidogenic processing under the influence of SORLA

• Main Authors: Dela Cruz, Michelle Andrea A., Tenio, Grazielle Joy C.
• Format: text
• Language: English
• Published: Animo Repository 2016
• Subjects: Amyloid beta-protein precursor; Stochastic processes
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/5892
• Institution: De La Salle University

Studies based on the amyloid hypothesis have shown that the proteolytic breakdown of amyloidogenic processing is the main pathology of Alzheimer's disease (AD). In this study, we focused on the effect of receptor SORLA, a 230 kDa type-1 transmembrane glycoprotein, after binding with the amyloid...