Interaction between the marine sponge cyclic peptide theonellamide A and sterols in lipid bilayers as viewed by surface plasmon resonance and solid-state 2H nuclear magnetic resonance

Theonellamides (TNMs) are members of a distinctive family of antifungal and cytotoxic bicyclic dodecapeptides isolated from the marine sponge Theonella sp. Recently, it has been shown that TNMs recognize 3β-hydroxysterol-containing membranes, induce glucan overproduction, and damage cellular membran...

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Main Authors: Espiritu, Rafael Atillo, Matsumori, Nobuaki, Murata, Michio, Nishimura, Shinichi, Kakeya, Hideaki, Matsunaga, Shigeki, Yoshida, Minuro
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Published: Animo Repository 2013
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/5118
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Institution: De La Salle University

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