Micronucleus assay of crude broccoli extract: Preliminary study on glucosinolates
Crude aqueous broccoli extracts were investigated for cancer chemopreventive potentials using the Micronucleus test with Mitomycin-C as reference mutagen. The experiment focused on the possible effect of the periof of intervention of the extract, at 48 hours and 71 hours of the 72-hour incubation pe...
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| Main Authors: | , , |
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| Format: | text |
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Animo Repository
2007
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/6049 |
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| Institution: | De La Salle University |
| Summary: | Crude aqueous broccoli extracts were investigated for cancer chemopreventive potentials using the Micronucleus test with Mitomycin-C as reference mutagen. The experiment focused on the possible effect of the periof of intervention of the extract, at 48 hours and 71 hours of the 72-hour incubation period. The extract did not exhibit mutagenic properties when used alone. Together with Mitomycin-C, however, the extract did exhibit significant antimutagenic behavior, lowering the micronucleus count to practically zero in some samples. These results bring one interesting finding: that the broccoli extracts have antimutagenic properties but are not mutagens themselves. |
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