Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

• Main Authors: Phipps, Richard Kerry, Shanmugham, Meenakshi Sundaram, Christensen, Louise Dahl, Jakobsen, Tim Holm, Gennip, Maria van, Alhede, Morten, Skindersoe, Mette Eline, Rasmussen, Thomas Bovbjerg, Friedrich, Karlheinz, Uthe, Friedrich, Jensen, Peter Østrup, Moser, Claus, Nielsen, Kristian Fog, Eberl, Leo, Larsen, Thomas Ostenfeld, Tanner, David, Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/100272; http://hdl.handle.net/10220/10960
• Institution: Nanyang Technological University

In relation to emerging multiresistant bacteria, development of antimicrobials and new treatment strategies of infections should be expected to become a high-priority research area. Quorum sensing (QS), a communication system used by pathogenic bacteria like Pseudomonas aeruginosa to synchronize the...