Nanobody mediated crystallization of an archeal mechanosensitive channel

• المؤلفون الرئيسيون: Moberg, Per, Quistgaard, Esben M., Löw, Christian, Yau, Yin Hoe, Pardon, Els, Jegerschöld, Caroline, Wåhlin, Lisa, Geifman-Shochat, Susana, Steyaert, Jan, Nordlund, Pär
• مؤلفون آخرون: Dryer, Stuart E.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/101386; http://hdl.handle.net/10220/18395

Mechanosensitive channels (MS) are integral membrane proteins and allow bacteria to survive sudden changes in external osmolarity due to transient opening of their pores. The efflux of cytoplasmic osmolytes reduces the membrane tension and prevents membrane rupture. Therefore these channels serve as...