Single vesicle analysis reveals nanoscale membrane curvature selective pore formation in lipid membranes by an antiviral α-helical peptide

Using tethered sub-100 nm lipid vesicles that mimic enveloped viruses with nanoscale membrane curvature, we have in this work designed a total internal reflection fluorescence microscopy-based single vesicle assay to investigate how an antiviral amphipathic α-helical (AH) peptide interacts with lipi...

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Bibliographic Details
Main Authors: Zhdanov, Vladimir P., Tabaei, Seyed R., Rabe, Michael, Cho, Nam-Joon, Höök, Fredrik
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/101429
http://hdl.handle.net/10220/11090
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Institution: Nanyang Technological University
Language: English