Frequent cases of RAS-mutated down syndrome acute lymphoblastic leukaemia lack JAK2 mutations

Frequent cases of RAS-mutated down syndrome acute lymphoblastic leukaemia lack JAK2 mutations

Children with Down syndrome (DS) and acute lymphoblastic leukaemia (ALL) have poorer survival and more relapses than non-DS children with ALL, highlighting an urgent need for deeper mechanistic understanding of DS–ALL. Here, using full-exome or cancer genes-targeted sequencing of 42 ALL samples from...

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書目詳細資料
Main Authors:	Nikolaev, Sergey I., Garieri, Marco, Santoni, Federico, Falconnet, Emilie, Ribaux, Pascale, Guipponi, Michel, Murray, Aoife, Groet, Jürgen, Giarin, Emanuela, Basso, Giuseppe, Nizetic, Dean, Antonarakis, Stylianos E.
其他作者:	Lee Kong Chian School of Medicine (LKCMedicine)
格式:	Article
語言:	English
出版:	2014
主題:	DRNTU::Science::Biological sciences::Human anatomy and physiology
在線閱讀:	https://hdl.handle.net/10356/101511 http://hdl.handle.net/10220/24153
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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