Pick one, but be quick : 5' splice sites and the problems of too many choices

• المؤلفون الرئيسيون: Roca, Xavier, Krainer, Adrian R., Eperon, Ian C.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/101529; http://hdl.handle.net/10220/18670
• المؤسسة: Nanyang Technological University

Splice site selection is fundamental to pre-mRNA splicing and the expansion of genomic coding potential. 5′ Splice sites (5′ss) are the critical elements at the 5′ end of introns and are extremely diverse, as thousands of different sequences act as bona fide 5′ss in the human transcriptome. Most 5′s...