X-Linked thrombocytopenia causing mutations in WASP (L46P and A47D) impair T cell chemotaxis
Background: Mutation in the Wiskott-Aldrich syndrome Protein (WASP) causes Wiskott-Aldrich syndrome (WAS), X-linked thrombocytopenia (XLT) and X-linked congenital neutropenia (XLN). The majority of missense mutations causing WAS and XLT are found in the WH1 (WASP Homology) domain of WASP, known to m...
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Main Authors: | Jain, Neeraj, Tan, Jun Hou, Feng, Shijin, George, Bhawana, Thanabalu, Thirumaran |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | https://hdl.handle.net/10356/101933 http://hdl.handle.net/10220/24212 |
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Institution: | Nanyang Technological University |
Language: | English |
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