Visualization of synaptic inhibition with an optogenetic sensor developed by cell-free protein engineering automation
We describe an engineered fluorescent optogenetic sensor, SuperClomeleon, that robustly detects inhibitory synaptic activity in single, cultured mouse neurons by reporting intracellular chloride changes produced by exogenous GABA or inhibitory synaptic activity. Using a cell-free protein engineering...
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| Main Authors: | , , , , , , |
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| 其他作者: | |
| 格式: | Article |
| 語言: | English |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://hdl.handle.net/10356/102024 http://hdl.handle.net/10220/18902 |
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| 機構: | Nanyang Technological University |
| 語言: | English |