Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone
Taking the Michael: The first highly enantio- and diastereoselective Michael addition of various 3-benzyl-substituted oxindoles to 2-cyclopentenone has been developed. A variety of 3,3-disubstituted oxindoles as Michael adducts were obtained in 69–99 % yield with 73–98 % ee and 9:1 to >20:1 d.r....
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sg-ntu-dr.10356-1021132020-03-07T12:31:25Z Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone Yang, Caiyun Chen, Wenchao Yang, Wenguo Zhu, Bo Yan, Lin Tan, Choon-Hong Jiang, Zhiyong School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Physical chemistry Taking the Michael: The first highly enantio- and diastereoselective Michael addition of various 3-benzyl-substituted oxindoles to 2-cyclopentenone has been developed. A variety of 3,3-disubstituted oxindoles as Michael adducts were obtained in 69–99 % yield with 73–98 % ee and 9:1 to >20:1 d.r. 2014-03-14T04:08:43Z 2019-12-06T20:49:55Z 2014-03-14T04:08:43Z 2019-12-06T20:49:55Z 2013 2013 Journal Article Yang, C., Chen, W., Yang, W., Zhu, B., Yan, L., Tan, C. H., et al. (2013). Bicyclic-Guanidine-Catalyzed Asymmetric Michael Addition of 3-Substituted Oxindoles to 2-Cyclopentenone. Chemistry - An Asian Journal, 8(12), 2960-2964. 1861-4728 https://hdl.handle.net/10356/102113 http://hdl.handle.net/10220/18901 10.1002/asia.201301011 en Chemistry - an Asian journal © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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DRNTU::Science::Chemistry::Physical chemistry Yang, Caiyun Chen, Wenchao Yang, Wenguo Zhu, Bo Yan, Lin Tan, Choon-Hong Jiang, Zhiyong Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| description |
Taking the Michael: The first highly enantio- and diastereoselective Michael addition of various 3-benzyl-substituted oxindoles to 2-cyclopentenone has been developed. A variety of 3,3-disubstituted oxindoles as Michael adducts were obtained in 69–99 % yield with 73–98 % ee and 9:1 to >20:1 d.r. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Yang, Caiyun Chen, Wenchao Yang, Wenguo Zhu, Bo Yan, Lin Tan, Choon-Hong Jiang, Zhiyong |
| format |
Article |
| author |
Yang, Caiyun Chen, Wenchao Yang, Wenguo Zhu, Bo Yan, Lin Tan, Choon-Hong Jiang, Zhiyong |
| author_sort |
Yang, Caiyun |
| title |
Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| title_short |
Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| title_full |
Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| title_fullStr |
Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| title_full_unstemmed |
Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| title_sort |
bicyclic-guanidine-catalyzed asymmetric michael addition of 3-substituted oxindoles to 2-cyclopentenone |
| publishDate |
2014 |
| url |
https://hdl.handle.net/10356/102113 http://hdl.handle.net/10220/18901 |
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1681036573816127488 |