Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors
Peptide-derived protease inhibitors are an important class of compounds with the potential to treat a wide range of diseases. Herein, we describe the synthesis of a series of triazole-containing macrocyclic protease inhibitors pre-organized into a β-strand conformation and an evaluation of their act...
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Main Authors: | Pehere, Ashok D., Pietsch, Markus, Gütschow, Michael, Neilsen, Paul M., Pedersen, Daniel Sejer, Nguyen, Steven, Zvarec, Ondrej, Sykes, Matthew J., Callen, David F., Abell, Andrew D. |
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Other Authors: | School of Materials Science & Engineering |
Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/102746 http://hdl.handle.net/10220/19119 |
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Institution: | Nanyang Technological University |
Language: | English |
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