Accurate detection of SNPs using base-specific cleavage and mass spectrometry

• Main Authors: Sun, Ruimin, Gao, Xiang, Han, Nanyu, Wu, Qiong, Mu, Yuguang, Tang, Kai, Chen, Xin
• Other Authors: School of Biological Sciences
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences; DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/102864; http://hdl.handle.net/10220/16876
• Institution: Nanyang Technological University

Accurate detection of single-nucleotide polymorphisms (SNPs) is crucial for the success of many downstream analyses such as clinical diagnosis, virus identification, genetic mapping and association studies. Among many others, one valuable approach for SNP detection is based on the base-specific clea...