Unraveling organocuprate complexity : fundamental insights into intrinsic group transfer selectivity in alkylation reactions

• Main Authors: Rijs, Nicole J., Yoshikai, Naohiko, Nakamura, Eiichi, O’Hair, Richard A. J.
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
• Online Access: https://hdl.handle.net/10356/103105; http://hdl.handle.net/10220/24362
• Institution: Nanyang Technological University

The near thermal conditions of an ion-trap mass spectrometer were used to examine the intrinsic gas-phase reactivity and selectivity of nucleophilic substitution reactions. The well-defined organocuprate anions [CH3CuR]– (R = CH3CH2, CH3CH2CH2, (CH3)2CH, PhCH2CH2, PhCH2, Ph, C3H5, and H) were reacte...