Adaptation of pandemic H2N2 influenza A viruses in humans

The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we per...

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Main Authors:	Joseph, Udayan, Linster, Martin, Suzuki, Yuka, Krauss, Scott, Halpin, Rebecca A., Vijaykrishna, Dhanasekaran, Fabrizio, Thomas P., Bestebroer, Theo M., Maurer-Stroh, Sebastian, Webby, Richard J., Wentworth, David E., Fouchier, Ron A. M., Bahl, Justin, Smith, Gavin J. D.
Other Authors:	Dermody, T. S.
Format:	Article
Language:	English
Published:	2015
Subjects:	DRNTU::Science::Biological sciences::Microbiology::Virology
Online Access:	https://hdl.handle.net/10356/103217 http://hdl.handle.net/10220/25774
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-103217
record_format	dspace
spelling	sg-ntu-dr.10356-1032172023-02-28T17:05:29Z Adaptation of pandemic H2N2 influenza A viruses in humans Joseph, Udayan Linster, Martin Suzuki, Yuka Krauss, Scott Halpin, Rebecca A. Vijaykrishna, Dhanasekaran Fabrizio, Thomas P. Bestebroer, Theo M. Maurer-Stroh, Sebastian Webby, Richard J. Wentworth, David E. Fouchier, Ron A. M. Bahl, Justin Smith, Gavin J. D. Dermody, T. S. School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology::Virology The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes. ASTAR (Agency for Sci., Tech. and Research, S’pore) Published version 2015-06-05T02:14:50Z 2019-12-06T21:07:41Z 2015-06-05T02:14:50Z 2019-12-06T21:07:41Z 2015 2015 Journal Article Joseph, U., Linster, M., Suzuki, Y., Krauss, S., Halpin, R. A., Vijaykrishna, D., et al. (2015). Adaptation of pandemic H2N2 influenza A viruses in humans. Journal of virology, 89(4), 2442-2447. https://hdl.handle.net/10356/103217 http://hdl.handle.net/10220/25774 10.1128/JVI.02590-14 25505070 en Journal of virology © 2015 American Society for Microbiology (ASM). This paper was published in Journal of Virology and is made available as an electronic reprint (preprint) with permission of American Society for Microbiology (ASM). The paper can be found at the following official DOI: [http://dx.doi.org/10.1128/JVI.02590-14]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 7 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Science::Biological sciences::Microbiology::Virology
spellingShingle	DRNTU::Science::Biological sciences::Microbiology::Virology Joseph, Udayan Linster, Martin Suzuki, Yuka Krauss, Scott Halpin, Rebecca A. Vijaykrishna, Dhanasekaran Fabrizio, Thomas P. Bestebroer, Theo M. Maurer-Stroh, Sebastian Webby, Richard J. Wentworth, David E. Fouchier, Ron A. M. Bahl, Justin Smith, Gavin J. D. Adaptation of pandemic H2N2 influenza A viruses in humans
description	The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes.
author2	Dermody, T. S.
author_facet	Dermody, T. S. Joseph, Udayan Linster, Martin Suzuki, Yuka Krauss, Scott Halpin, Rebecca A. Vijaykrishna, Dhanasekaran Fabrizio, Thomas P. Bestebroer, Theo M. Maurer-Stroh, Sebastian Webby, Richard J. Wentworth, David E. Fouchier, Ron A. M. Bahl, Justin Smith, Gavin J. D.
format	Article
author	Joseph, Udayan Linster, Martin Suzuki, Yuka Krauss, Scott Halpin, Rebecca A. Vijaykrishna, Dhanasekaran Fabrizio, Thomas P. Bestebroer, Theo M. Maurer-Stroh, Sebastian Webby, Richard J. Wentworth, David E. Fouchier, Ron A. M. Bahl, Justin Smith, Gavin J. D.
author_sort	Joseph, Udayan
title	Adaptation of pandemic H2N2 influenza A viruses in humans
title_short	Adaptation of pandemic H2N2 influenza A viruses in humans
title_full	Adaptation of pandemic H2N2 influenza A viruses in humans
title_fullStr	Adaptation of pandemic H2N2 influenza A viruses in humans
title_full_unstemmed	Adaptation of pandemic H2N2 influenza A viruses in humans
title_sort	adaptation of pandemic h2n2 influenza a viruses in humans
publishDate	2015
url	https://hdl.handle.net/10356/103217 http://hdl.handle.net/10220/25774
_version_	1759854111369461760

Adaptation of pandemic H2N2 influenza A viruses in humans

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