Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis

Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis

Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E) gene attenuates the virus. E gene encodes a small multifunctional protein that possesses ion channel (IC) activity, an important function in virus-host interaction. To test the contribution of E protein IC activity in...

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Bibliographic Details
Main Authors: Verdiá-Báguena, Carmina, Castaño-Rodriguez, Carlos, Alcaraz, Antonio, Torres, Jaume, Enjuanes, Luis, Fernandez-Delgado, Raul, Nieto-Torres, Jose L., DeDiego, Marta L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Aguilella, Vicente M.
Other Authors: Denison, Mark R.
Format: Article
Language:English
Published: 2014
Subjects:
Biological Sciences
Online Access:https://hdl.handle.net/10356/103424
http://hdl.handle.net/10220/20005
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/103424
http://hdl.handle.net/10220/20005

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