Inhibition of 3-D tumor spheroids by timed-released hydrophilic and hydrophobic drugs from multilayered polymeric microparticles

First-line cancer chemotherapy necessitates high parenteral dosage and repeated dosing of a combination of drugs over a prolonged period. Current commercially available chemotherapeutic agents, such as Doxil and Taxol, are only capable of delivering single drug in a bolus dose. The aim of this study...

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Main Authors: Tan, Ern Yu, Loo, Say Chye Joachim, Lee, Wei Li, Guo, Wei Mei, Ho, Vincent H. B., Saha, Amitaksha, Chong, Han Chung, Tan, Nguan Soon, Widjaja, Effendi
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103481
http://hdl.handle.net/10220/24526
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Institution: Nanyang Technological University
Language: English